119-47-1

Basic information

• Product Name: 2,2'-Methylenebis(6-tert-butyl-4-methylphenol)
• Synonyms: 2,2’-bis;2,2’-bis(6-t-butyl-p-cresyl)-methan;2,2’-bis(6-t-butyl-p-cresyl)-methane;2,2’-bis-6-terc.butyl-p-kresylmethan;2,2’-bis-6-terc.butyl-p-kresylmethan(czech);2,2’-methylenebis(6-(1,1-dimethylethyl)-4-methyl-pheno;2,2’-methylenebis(6-tert-butyl-p-creso;2,2’-methylenebis[6-(1,1-dimethylethyl)-4-methyl-pheno
• CAS NO: 119-47-1
• Molecular Formula: C₂₃H₃₂O₂
• Molecular Weight: 340.5
• EINECS: 204-327-1
• Product Categories: Industrial/Fine Chemicals;Organics;Diphenylmethanes (for High-Performance Polymer Research);Functional Materials;Reagent for High-Performance Polymer Research;Polymer Additives;Polymer Science;Stabilizers;mildew preventive;Antioxidant
• Mol File: 119-47-1.mol
• Article Data: 52

Chemical Properties

• Melting Point: 123-127 °C(lit.)
• Boiling Point: 187℃
• Flash Point: 195°C(383°F)
• Appearance: white to pale creamy crystalline powder
• Density: 1.04g/cm3
• Vapor Pressure: <1 hPa
• Refractive Index: 1.4480 (estimate)
• Storage Temp.: Store below +30°C.
• Solubility: 0.007mg/l practically insoluble
• PKA: 11.32±0.48(Predicted)
• Water Solubility: 7μg/L at 20℃
• CAS DataBase Reference: 2,2'-Methylenebis(6-tert-butyl-4-methylphenol)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-Methylenebis(6-tert-butyl-4-methylphenol)(119-47-1)
• EPA Substance Registry System: 2,2'-Methylenebis(6-tert-butyl-4-methylphenol)(119-47-1)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36-62-53
• Safety Statements: 26-36-60-36/37
• WGK Germany: 1
• RTECS: PA3500000
• TSCA: Yes
• Hazardous Substances Data: 119-47-1(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 119-47-1 differently. You can refer to the following data:
1. LOWINOX? 22M46 stabilizer is a non-discoloring antioxidant based on a sterically hindered alkylated bis-phenol.
2. It may be incorporated into the bromobutyl rubber(BIIR) matrix to enhance the overall thermo-reversibility of dicyclopentadiene dicarboxylic acid (DCPDCA) cross-linked BIIR. It may also be used as an antioxidant which shows a higher oxidation stability in distilled biodiesel.

General Description

2,2′-Methylenebis(6-tert-butyl-4-methylphenol) is a phenolic antioxidant commonly used in increasing the oxidation stability in rubber and plastic industries.

Flammability and Explosibility

Notclassified

Properties and Applications

TEST ITEMS SPECIFICATION APPEARANCE COLORLESS CRYSTALLINE POWDER CONTENT 98.0% min MELTING POINT 124 °C + MELTING RANGE 120-130 °C VOLATILE 0.3% max ASH 0.1% max 150um SIEVE RESIDUE 0.5% max

TEST ITEMS

SPECIFICATION

APPEARANCE

COLORLESS CRYSTALLINE POWDER

CONTENT

98.0% min

MELTING POINT

124 °C +

MELTING RANGE

120-130 °C

VOLATILE

0.3% max

ASH

0.1% max

150um SIEVE RESIDUE

0.5% max

Synthetic route

formaldehyd (50-00-0) + p-cresol (106-44-5) + tert-butyl methyl ether (1634-04-4) → 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1)

Conditions	Yield
With sulfonated multi-walled carbon nanotubes In neat (no solvent) at 100℃; for 2.5h; Catalytic behavior; regiospecific reaction;	100%

Dimethoxymethane (109-87-5) + 2-tert-Butyl-4-methylphenol (2409-55-4) → 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1)

Conditions	Yield
With acid clay at 170℃; for 2h; Reagent/catalyst; Temperature;	97%
With sulfuric acid at 60 - 70℃; for 2h;	70%
With cation exchanger KU-2; sulfuric acid at 100℃; for 3h; Kinetics; Mechanism; Rate constant; other time, other temperature;

formaldehyd (50-00-0) + 2-tert-Butyl-4-methylphenol (2409-55-4) → 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1)

Conditions	Yield
With sodium tetramethoxyborate In dimethyl sulfoxide at 150℃; for 0.5h; Reagent/catalyst; Temperature; Solvent;	95%
In xylene at 175℃; for 10h;	85%
With montmorillonite KSF In octane for 2h; Reflux;	79%

formaldehyd (50-00-0) + 2,4-di-tert-Butylphenol (96-76-4) → 2,2'-methylenebis(4,6-di-tert-butylphenol) (14362-12-0) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1)

Conditions	Yield
With montmorillonite KSF In n-heptane for 2h; Reflux;	A 85% B 77%

formaldehyd (50-00-0) + 2-tert-Butyl-4-methylphenol (2409-55-4) → 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + 8-tert-butyl-6-methyl-4H-benzo[1,3]dioxine

Conditions	Yield
In toluene at 100℃; for 1h; Condensation; acetalisation;	A 35% B 48%

Dimethoxymethane (109-87-5) + 2-tert-Butyl-4-methylphenol (2409-55-4) → 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + 2-(tert-butyl)-6-(methoxymethyl)-4-methylphenol (4103-77-9)

Conditions	Yield
With ion-exchange resin at 100℃; Product distribution;

formaldehyde diethyl acetal (462-95-3) + 2-tert-Butyl-4-methylphenol (2409-55-4) → 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + 2-ethoxymethyl-4-methyl-6-tert-butylphenol

Conditions	Yield
With ion-exchange resin at 100℃; Product distribution;

2-tert-Butyl-4-methylphenol (2409-55-4) + 2-(tert-butyl)-6-(methoxymethyl)-4-methylphenol (4103-77-9) → 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1)

Conditions	Yield
With cation exchanger KU-2; sulfuric acid at 100℃; for 3h; Kinetics; Mechanism; Rate constant; other time, other temperature;

p-cresol (106-44-5) → 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1)

Conditions	Yield
Multi-step reaction with 2 steps 1: sulfuric acid / 60 °C 2: aq.-ethanolic HCl View Scheme

Dimethoxymethane (109-87-5) + 2-tert-Butyl-4-methylphenol (2409-55-4) + sulfuric acid (7664-93-9) → 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1)

5,11,17,23-tetratert-butyl-4,12,16,24-tetrahydroxycalix[4]arene ethanol complex → 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1)

Conditions	Yield
at 100℃;

6-tert-butyl-2-(2'-methoxy-3'-tert-butyl-5'-methylbenzyl)-4-methylphenol (27996-19-6) → 2-tert-Butyl-6-methylphenol (2219-82-1) + 2,4-dimethyl-6-tert-butylphenol (1879-09-0) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1)

Conditions	Yield
With zinc(II) oxide; sodium hydroxide In methanol at 220℃; for 4h;

(2S)-2-(6-methoxy(2-naphthyl))propanoic acid (22204-53-1) → 1-methoxy-2-propanol (107-98-2) + Hexadecane (544-76-3) + 2,6-di-tert-butyl-4-methyl-phenol (128-37-0) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + NSC 59850 (2138-49-0)

Conditions	Yield
With montmorillonite K10-immobilized ZnO nanocomposite pH=4.5; Catalytic behavior; Reagent/catalyst; pH-value; Concentration; Sonication;

2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + titanium(IV)isopropoxide (546-68-9) → bis(2,2'-methylene-bis(6-t-butyl-4-methylphenoxide))titanium (161810-86-2)

Conditions	Yield
In diethyl ether Ar atmosphere, addn. of Ti compound to soln. of phenol at room temp., stirring (room temp., 2 h); removement of volatiles, drying (120°C); elem. anal.;	99%

tetrahydrofuran (109-99-9) + tris(cyclopentadienyl)neodymium + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → (cyclopentadienyl)Nb(2,2'-methylenebis(6-tert-butyl-4-methylphenoxo))(tetrahydrofuran)2 (860400-33-5)

Conditions	Yield
In tetrahydrofuran (Ar); a soln. of ligand added slowly to a soln. of Nd complex, stirred for 1 h at 40°C; evapd. (vac.), extd. (toluene), crystd. at -10°C; elem. anal.;	99%

tetrahydrofuran (109-99-9) + (cyclopentadienyl)3Y(THF) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → CpY(2,2'-methylene-bis(6-tert-butyl-4-methyl-phenoxo)(tetrahydrofuran)2 (1076233-65-2)

Conditions	Yield
In tetrahydrofuran under Ar; a THF soln. of a ligand (4.50 mmol) was slowly added to a THF soln. of Y-contg. compd. (3.45 mmol); the mixt. was stirred for 6 h at 50°C; the solvent was removed under vac.; toluene was added; crystals were obtained from toluene at -5°C; elem. anal.;	99%

+ 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → diethylamido-O-(2-[2-hydroxy-3-tert-butyl-5-methylbenzyl]-4-methyl-6-tert-butyl-phenyl)-O-phenylphosphite

Conditions	Yield
In acetonitrile at 75℃; for 1.5h;	98%

2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + titanium tetramethoxide (992-92-7) → dimethoxy[2,2'-methylenebis(6-tert-butyl-4-methylphenoxy)]titanium (161810-84-0)

Conditions	Yield
In hexane Ar atmosphere, stirring (room temp., 3 d); filtration, washing (hexane), drying (vacuum); elem. anal.;	97%

2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + N,N'-bis(dichlorophosphino)aniline (39652-40-9) → 7,15-di-tert-butyl-10,12-dichloro-5,17-dimethyl-11-phenyl-9,13-dioxa-11-aza-10,12-diphospha-tricyclo[12.4.0.03,8]octadeca-1(18),3(8),4,6,14,16-hexaene

Conditions	Yield
With triethylamine In tetrahydrofuran at -5 - 25℃;	95%

2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + acrylic acid (79-10-7) → 2-(2-hydroxy-3-tert-butyl-5-methylbenzyl)-4-methyl-6-tert-butylphenyl acrylate (61167-58-6)

Conditions	Yield
With triethylamine; trichlorophosphate In nitrogen; toluene	95%

2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + acryloyl chloride (814-68-6) → 2-(2-hydroxy-3-tert-butyl-5-methylbenzyl)-4-methyl-6-tert-butylphenyl acrylate (61167-58-6)

Conditions	Yield
With triethylamine In nitrogen; toluene	95%
With triethylamine In nitrogen; toluene	72.7%

2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + trimethylaluminum (75-24-1) → bis[Al(methyl)(2,2'-methylenebis(6-tert-butyl-4-methylphenolato))] complex (264910-30-7)

Conditions	Yield
In hexane byproducts: CH4; under Ar, std. Schlenk or glovebox techniques; soln. of Al(CH3)3 added slowly; heat observed; mixt. cooled; ppt. filtered off; washed with cold hexane; dried in vac.; elem. anal.;	95%
In hexane; toluene under Ar; 2 M soln. of AlMe3 in hexane added to soln. of bis(phenol) in toluene at room temp. (molar ratio = 1:1), mixt. stirred for 5 h; solid filtered off and washed twice with hexane; elem. anal.;	65%
In hexane; toluene Ar; hexane soln. of AlMe3 added to toluene/hexane soln. of ligand (1:1 molar ratio) at -78°C, slowly warmed to room temp., stirred for 8 h under O2; ppt. filtered off, washed (hexane), elem. anal.;	52%

2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → C23H31O2(1-)*Na(1+)*4C4H8O

Conditions	Yield
With sodium In tetrahydrofuran at 20℃; for 12h; Inert atmosphere;	95%

poly(methacrylic acid) (79-41-4) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + 2-(2-hydroxy-3-tert-butyl-5-methylbenzyl)-4-methyl-6-tert-butylphenyl acrylate (61167-58-6) + Toluene-2-sulfonyl chloride (133-59-5) → 2-t-butyl-6-[1-(3-t-butyl-2-hydroxy-5-methylphenyl)ethyl]-4-methylphenyl acrylate (61167-60-0)

Conditions	Yield
With triethylamine In nitrogen; toluene	94%

methanol (67-56-1) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → 2,4-dimethyl-6-tert-butylphenol (1879-09-0)

Conditions	Yield
With zinc(II) oxide; sodium hydroxide at 250℃; for 8h;	94%

tetrahydrofuran (109-99-9) + methanol (67-56-1) + tris(cyclopentadienyl)neodymium + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → [(2,2'-methylenebis(6-tert-butyl-4-methylphenoxo))Nd(μ-OMe)(tetrahydrofuran)2]2 (860400-38-0)

Conditions	Yield
In tetrahydrofuran (Ar); a soln. of 2,2'-methylenebis(6-tert-butyl-4-methylphenol) added slowly to a soln. of Nd complex at 40°C, stirred for 1 h at 40°C, methanol added, stirred overnight at room temp.; centrifuged; also isolated from the concd. soln.; elem. anal.;	93%

2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + titanium(IV)isopropoxide (546-68-9) → methylenebis(6-tert-butyl-4-methylphenoxy-2-yl) diisopropoxytitanium(IV) (134754-21-5)

Conditions	Yield
In diethyl ether Ar atmosphere, addn. of soln. of phenol to soln. of Ti compound at 0°C; concn., crystn. (-20°C), filtration; elem. anal.;	92%

tetrahydrofuran (109-99-9) + tris(η5-cyclopentadienyl)lantanum(III) tetrahydrofuran + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → CpLa(2,2'-methylene-bis(6-tert-butyl-4-methyl-phenoxo)(tetrahydrofuran)3 (1076233-63-0)

Conditions	Yield
In tetrahydrofuran under Ar; a THF soln. of a ligand (4.50 mmol) was slowly added to a THF soln. of La-contg. compd. (3.00 mmol); the mixt. was stirred for 6 h at 50°C; the solvent was removed under vac.; toluene was added; crystals were obtained from toluene at -5°C; elem. anal.;	92%

2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + titanium tetrachloride (7550-45-0) → methylenebis(6-tert-butyl-4-methylphenoxy-2-yl) dichlorotitanium(IV) (118538-56-0)

Conditions	Yield
In hexane Ar atmosphere, addn. of TiCl4 to soln. of phenol, stirring (room temp., 24 h); crystn. (-20°C, 18 h), filtration, drying (vacuum); elem. anal.;	91%
In hexane byproducts: HCl; TiCl4 was dropped to a soln. of MBPH2 in hexane. After 12 h standing at room temp. red crystals are formed.;	88%
In hexane byproducts: HCl; under nitrogen, stirring for 12 h; filtration, washing with pentane;	88%
In hexane at -40 - 20℃; for 16h;	69%

diethyl ether (60-29-7) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + triisobutylaluminum (100-99-2) → (diethyl ether)-isobutyl-(2,2'-methylene-bis(4-methyl-6-tert-butylphenolato))aluminum(III) (251310-97-1)

Conditions	Yield
In diethyl ether; hexane dry N2-atmosphere; addn. of Al-i-Bu3 (in hexane) to 1 equiv. ligand (in Et2O) at 0°C, stirring for 2 h; evapn. (vac.), extn. into Et2O, filtration, concn., crystn. (4°C); elem. anal.;	91%
In diethyl ether byproducts: isobutane; under Ar; soln. of 2,2'-methylene-bis(6-tert-butyl-4-methylphenol) added to soln. of triisobutylaluminum (5 min, room temp.); stirred (2 h); ether removed; solid recrystd. (Et2O); elem.anal.;	63%

borane-THF (14044-65-6) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → 4,8-di-tert-butyl-2,10-dimethyl-12H-dibenzo[d,g][1,3,2]dioxaborocine (188707-76-8)

Conditions	Yield
In tetrahydrofuran byproducts: H2; (N2); after stirring in THF removal of volatiles in vacuo and heating to100°C for 90 min; crystn. (hexane); elem. anal.;	91%

[Sm(tetramethylaluminate)2]n + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → (Sm(μ-η6'-[6,6'-methylenebis(2-tert-butyl-4-methylphenoxy)][AlMe2])(μ-Me)2(AlMe))(μ-Me)

Conditions	Yield
In toluene under N2; soln. of ligand in toluene added to suspn. of Sm(AlMe4)2 in toluene; brought to boiling; vol. reduced; cooled to room temp.; crystd. for 24 h; elem. anal.;	91%

tetrahydrofuran (109-99-9) + tris(cyclopentadienyl)(tetrahydrofuran)samarium(III) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → (C5H5)Sm(2,2′-methylene-bis(6-tert-butyl-4-methylphenolate))(THF)2

Conditions	Yield
at 50℃; for 6h; Schlenk technique; Inert atmosphere;	91%

bis[N,N-bistrimethylsilylamido]bis(tetrahydrofuran)ytterbium(II) (154671-38-2) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → bis(2,2'-methylenebis(6-tert-butyl-4-methylphenolate))tetrakis(tetrahydrofuran)diytterbium(II) (697278-07-2)

Conditions	Yield
In hexane; toluene under Ar; addn. of a soln. of ytterbium complex in hexane to a soln. of ligand in toluene, stirring at room temp. for 5 h; centrifugation, ppt. washed with hexane; elem. anal.;	90.1%

methanol (67-56-1) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + trimethyl indium (3385-78-2) → [Me6In3(OMe)(2,2'-methylenebis(4-methyl-6-tert-butylphenolate)] (1187925-67-2)

Conditions	Yield
In methanol; diethyl ether byproducts: CH4; (N2); std. Schlenk technique; soln. of MeOH in Et2O was added to stirredsoln. of Me3In in Et2O at -76°C; warmed to room temp.; soln. of ligand in Et2O was added at -76°C; filtered; washed (Et2O); dried (vac.); elem. anal.;	90%

N,N,N,N,N,N-hexamethylphosphoric triamide (680-31-9) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → (4,8-di-tert-butyl-2,10-dimethyl-12H-5,7-dioxa-6-phosphadibenzo[a,d]cycloocten-6-yl)dimethylamine

Conditions	Yield
In toluene at 20 - 100℃; Inert atmosphere;	90%

2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → 4,8-di-tert-butyl-2,10-dimethyl-12H-dibenzo[d,g][1,3,2]dioxaborocine (188707-76-8)

Conditions	Yield
With dimethylsulfide borane complex In toluene for 18h; Reflux;	90%

2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) + dimethyl sulfide borane (13292-87-0) → 4,8-di-tert-butyl-2,10-dimethyl-12H-dibenzo[d,g][1,3,2]dioxaborocine (188707-76-8)

Conditions	Yield
In toluene under N2; phenol-compd. added to B-compd. in toluene, heated at reflux for 18 h;	90%

Sm(N(SiMe3)2)2(THF)2 (112068-81-2) + 2,2'-dihydroxy-5,5'-dimethyl-3,3'-di-tert-burtyl-1,1'-diphenylmethane (119-47-1) → bis(2,2'-methylenebis(6-tert-butyl-4-methylphenolate))hexakis(tetrahydrofuran)disamarium(II) (697278-06-1)

Conditions	Yield
In hexane; toluene under Ar; addn. of a soln. of samarium complex in hexane to a soln. of ligand in toluene, stirring at room temp. for 5 h; centrifugation, ppt. washed with hexane; elem. anal.;	89.6%

Upstream product

• 50-00-0 formaldehyd 
• 2409-55-4 2-tert-Butyl-4-methylphenol 
• 109-87-5 Dimethoxymethane 
• 462-95-3 formaldehyde diethyl acetal 
• 4103-77-9 2-(tert-butyl)-6-(methoxymethyl)-4-methylphenol 
• 106-44-5 p-cresol 
• 27996-19-6 6-tert-butyl-2-(2'-methoxy-3'-tert-butyl-5'-methylbenzyl)-4-methylphenol 
• 22204-53-1 (2S)-2-(6-methoxy(2-naphthyl))propanoic acid 
• 1634-04-4 tert-butyl methyl ether 
• 96-76-4 2,4-di-tert-Butylphenol 
• 7664-93-9 sulfuric acid 

Downstream Products

• 27996-19-6 6-tert-butyl-2-(2'-methoxy-3'-tert-butyl-5'-methylbenzyl)-4-methylphenol 
• 54519-39-0 bis(2-methoxy-3-tert-butyl-5-methylphenyl)methane 
• 282716-78-3 C₄₁H₆₉N₃O₆P₂ 
• 282716-80-7 C₆₀H₉₀N₂O₈P₂ 
• 109-89-7 diethylamine 
• 295805-67-3 bis[3-tert-butyl-5-methyl-2-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yloxy)phenyl]methane 
• 32604-47-0 Bis-<2-acetoxy-3-tert.butyl-5-methyl-phenyl)-methan 
• 203255-71-4 2,4,8,10-tetra-t-butyl-6-[3-(3,5-di-t-butyl-4-hydroxyphenyl)propoxyl]dibenzo[d,f][1,3,2]dioxaphosphepine 
• 860400-43-7 [(2,2'-methylenebis(6-tert-butyl-4-methylphenoxo))Yb(μ-OCH2Ph)(tetrahydrofuran)2]2 
• 860400-41-5 [(2,2'-methylenebis(6-tert-butyl-4-methylphenoxo))Nd(μ-OCH2Ph)(tetrahydrofuran)2]2 
• 1266658-23-4 (E)-4,8-ditert-butyl-6-(4-methoxystyryl)-2,10-dimethyl-12H-dibenzo[d,g][1,3,2]dioxaborocine 
• 1266658-24-5 (E)-4,8-ditert-butyl-6-(4-fluorostyryl)-2,10-dimethyl-12H-dibenzo[d,g][1,3,2]dioxaborocine 
• 1266658-25-6 (E)-4,8-ditert-butyl-6-(2,4,6-trimethylstyryl)-2,10-dimethyl-12H-dibenzo[d,g][1,3,2]dioxaborocine 
• 1266658-26-7 (E)-4,8-di-tert-butyl-2,10-dimethyl-6-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)styryl)-12H-dibenzo[d,g][1,3,2]dioxaborocine 

Relevant articles and documents

Regiospecific, one-pot, and pseudo-five-component synthesis of 6,6′-(arylmethylene)bis(2-(tert -butyl)4-methylphenol) antioxidants using highly sulfonated multi-walled carbon nanotubes under solvent-free conditions

This is the first report of an innovative, one-pot, pseudo-five-component, and solvent-free synthesis of 6,6′-(arylmethylene)bis(2-(tert-butyl)4- methylphenol) antioxidants from p-cresol, methyl tert-butyl ether, and aldehydes in the presence of sulfonate

Trialkylamine controlled phenol-for maldehyde reaction over clay catalysts: Selective and environmentally benign synthesis of salicylic aldehydes

Substituted salicylic aldehydes 6 are synthesised in good yields and excellent selectivities by reaction of phenols 1 with formaldehyde 2 over montmorillonite KSF-Et3N as a heterogeneous and reusable catalyst. (C) 2000 Elsevier Science Ltd.

Antioxidant bisphenol compounds clean production method and application (by machine translation)

The invention discloses a double-phenolic compound antioxidant clean production process and application. The clean production method comprises: in a solid acid catalyst, and in order to aliphatic aldehyde and dialkyl substituted phenol as raw material, the raw material and the catalyst is placed in a closed environment reaction, and the reaction of the reaction product after the end of filter heat, that is, to obtain the target product, which can be used for preparing lubricating oil composition or as a plastic, rubber, such as anti-aging agent. Antioxidant bisphenol compounds of this invention for the production of simple operation, mild conditions, such as the sources of the raw materials and catalyst, is cheap and easy to obtain, the reaction cycle is short, it is easy to control, process with high safety, low energy consumption in the producing process, high yield, high purity of the product, in the reaction process does not need to add water, organic solvent, surface active agent, there is no need to wash the product later, will not produce waste water, can greatly control and reducing pollutant emissions, is a safe and energy-saving, environmental protection art. (by machine translation)

Sonocatalytic removal of naproxen by synthesized zinc oxide nanoparticles on montmorillonite

ZnO/MMT nanocomposite as sonocatalyst was prepared by immobilizing synthesized ZnO on the montmorillonite surface. The characteristics of as-prepared nanocomposite were studied by scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HR-TEM) and X-ray diffraction (XRD) techniques. The synthesized samples were used as a catalyst for sonocatalytic degradation of naproxen. ZnO/MMT catalyst in the presence of ultrasound irradiation was more effective compared to pure ZnO nanoparticles and MMT particles in the sonocatalysis of naproxen. The effect of different operational parameters on the sonocatalytic degradation of naproxen including initial drug concentration, sonocatalyst dosage, solution pH, ultrasonic power and the presence of organic and inorganic scavengers were evaluated. It was found that the presence of the scavengers suppressed the sonocatalytic degradation efficiency. The reusability of the nanocomposite was examined in several consecutive runs, and the degradation efficiency decreased only 2% after 5 repeated runs. The main intermediates of naproxen degradation were determined by gas chromatography-mass spectrometry (GC-Mass).