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Action mechanism of 6h for anti-proliferation of NCI-H522 non-small cell lung cancer cells. (A) Compound 6h, vincristine, vinblastine, and paclitaxel were incubated with pure tubulin proteins in GPEm buffer. Alternation of tubulin assembly was recorded at
Effect of compounds 6c–f on paclitaxel-induced tubulin assembly.
β-Amino acids in bioactive compounds:Paclitaxel, Sitagliptin, Loracarbef, Jasplakinolide, Bestatin.
