499-83-2Relevant articles and documents
Selective and sensitive fluorescent chemosensors for Cu2+ ion based upon bis-1,8-naphthalimide dyads
Dai, Huiling,Xu, Hui
, p. 267 - 272 (2012)
A series of new fluorescent chemosensors 5a-5e, composed of two aminonaphthalimide fluorophores and 2,6-bis((N-aminoalkyl)aminocarboxy) pyridines, were prepared, characterized, and their fluorescent properties towards heavy and transition metal (HTM) ions were investigated. Chemosensors 5c-5e exhibited high selectivity and sensitivity for Cu2+ ion over other HTM ions with fluorescent quenching (green to colourless). It clearly demonstrated that the length of the linkers (diamines) between the aminonaphthalimides and 2,6-dicarboxypyridine of 5a-5e was very important for their sensitivity and selectivity for Cu2+ ion over other HTM ions. Three chemosensors 5c-5e exhibited high selectivity and sensitivity for Cu 2+ ion over other heavy and transition metal ions with fluorescent quenching (green to colourless). Copyright
Bis(hydroxylamino)triazines: High Selectivity and Hydrolytic Stability of Hydroxylamine-Based Ligands for Uranyl Compared to Vanadium(V) and Iron(III)
Hadjithoma, Sofia,Papanikolaou, Michael G.,Leontidis, Epameinondas,Kabanos, Themistoklis A.,Keramidas, Anastasios D.
, p. 7631 - 7643 (2018)
The development of ligands with high selectivity and affinity for uranium is critical in the extraction of uranium from human body, radioactive waste, and seawater. A scientific challenge is the improvement of the selectivity of chelators for uranium over other heavy metals, including iron and vanadium. Flat ligands with hard donor atoms that satisfy the geometric and electronic requirements of the UVIO22+ exhibit high selectivity for the uranyl moiety. The bis(hydroxylamino)(triazine) ligand, 2,6-bis[hydroxy(methyl)amino]-4-morpholino-1,3,5-triazine (H2bihyat), a strong binder for hard metal ions (FeIII, TiIV, VV, and MoVI), reacted with [UVIO2(NO3)2(H2O)2]·4H2O in aqueous solution and resulted in the isolation of the complexes [UVIO2(bihyat)(H2O)], [UVIO2(bihyat)2]2-, and {[UVIO2(bihyat)(μ-OH)]}22-. These three species are in equilibrium in aqueous solution, and their abundance varies with the concentration of H2bihyat and the pH. Reaction of H2bihyat with [UVIO2(NO3)2(H2O)2]·4H2O in CH3CN gave the trinuclear complex [UVI3O6(bihyat)2(μ-bihyat)2]2-, which is the major species in organic solvents. The dynamics between the UVIO22+ and the free ligand H2bihyat in aqueous and dimethyl sulfoxide solutions; the metal binding ability of the H2bihyat over pyridine-2,6-dicarboxylic acid (H2dipic) or glutarimidedioxime for UVIO22+, and the selectivity of the H2bihyat to bind UVIO22+ in comparison to VVO43- and FeIII in either UVIO22+/VVO43- or UVIO22+/FeIII solutions were examined by NMR and UV-vis spectroscopies. The results revealed that H2bihyat is a superior ligand for UVIO22+ with high selectivity compared to FeIII and VVO43-, which increases at higher pHs. Thus, this type of ligand might find applications in the extraction of uranium from the sea and its removal from the environment and the human body.
A novel synthesis of 2,6-pyridinedicarboxylic acid by the PTC auto-oxidation of 2,6-lutidine
Iovel,Shymanska
, p. 2691 - 2596 (1992)
2,6-Pyridinedicarboxylic acid was obtained in 69% yield by the oxidation of 2,6-dimethylpyridine with oxygen under the action of tert-BuOK in the presence of the phase-transfer catalyst 18-crown-6.
High efficiency co-sensitized solar cell based on luminescent lanthanide complexes with pyridine-2,6-dicarboxylic acid ligands
Wang, Xin,Yang, Yu-Lin,Wang, Ping,Li, Liang,Fan, Rui-Qing,Cao, Wen-Wu,Yang, Bin,Wang, Hui,Liu, Jing-Yao
, p. 10619 - 10625 (2012)
Two lanthanide complexes, Ln(HPDA)3·4EtOH (Ln = Tb, Dy) (H2PDA = pyridine-2,6-dicarboxylic acid, EtOH = ethanol), have been successfully synthesized using hydrothermal or solvothermal methods, and their crystal structures were analyz
Preparation method of 2,6-chloromethylpyridine hydrochloride (by machine translation)
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Paragraph 0018; 0021; 0022; 0026; 0027; 0031; 0032, (2020/03/03)
The invention belongs to the field, of organic synthesis, and particularly relates to 2,6 -chloromethylpyridine hydrochloride, preparation method :(1), which comprises the following steps 2,6 - reacting,dimethylaminopyridine as a raw material 2,6 - to prepare ;(2)2,6 -picolinic acid dimethyl 2,6 -picolinic acid dimethyl ;(3)2,6 -pyridine dimethanol and thionyl chloride to obtain a target product 2,6 -dichloromethylpyridine dihydrochloride with methanol in an acidic condition ;(4)2,6 - The method comprises the following steps: reacting 2,6 - with a commonly-used chemical raw material containing a pyridine ring and methanol in an acidic condition. The method disclosed by the invention is suitable for industrial, production : (by machine translation)
A 2, 6 - dichloro methyl pyridine hydrochloride preparation method (by machine translation)
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Paragraph 0021-0022; 0026-0027, (2019/05/28)
The invention belongs to the field of organic synthesis, in particular relates to a 2, 6 - dichloro methyl pyridine hydrochloride of the preparation method, the method comprises the following steps: (1) to 2, 6 - lutidine as a raw material, preparation 2, 6 - pyridine dicarboxylic acid; (2) 2, 6 - pyridine dicarboxylic acid with methanol under acidic conditions to produce the 2, 6 - pyridine dicarboxylic acid dimethyl ester; (3) 2, 6 - pyridine dicarboxylic acid dimethyl ester is reduced to 2, 6 - pyridine-methanol; (4) 2, 6 - pyridine-methanol with thionyl chloride reaction to obtain the target product 2, 6 - dichloro methyl pyridine hydrochloride. The beneficial effect of the invention is: the invention adopts the commonly used chemical raw materials containing a pyridine [...] reaction, reaction steps is small, low cost, low toxicity, high yield, it is suitable for industrial production. (by machine translation)
Preparation method of 2,6-pyridinedicarboxylic acid
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Paragraph 0048-0053, (2019/10/01)
The invention provides a preparation method of 2,6-pyridinedicarboxylic acid. The preparation method comprises the following steps: taking 1,7-pimelic acid or 1,7-pimelic acid diester (I) as a raw material to carry out a halogenation reaction to obtain 2,2,6,6-tetrahalide (II), then carrying out a cyclization reaction with ammonia to prepare a dihydropyridine derivative (III), and carrying out oxidation by an oxidizing agent or carrying out oxidation-hydrolysis to obtain the 2,6-pyridinedicarboxylic acid. According to the method disclosed by the invention, raw materials are cheap and easily available, and the preparation method is simple, is easy to implement, and is safe and environmentally friendly. The amount of wastewater is small, cost is low, the yield and selectivity are high, byproducts are fewer, and the preparation method is suitable for industrial production.
Method for synthesizing 2,6-dipicolinic acid
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Paragraph 0020; 0021, (2017/02/09)
The invention discloses a method for synthesizing 2,6-dipicolinic acid. The method comprises the following steps: under the condition of air isolation, by using anhydrous diethyl ether or THF (tetrahydrofuran) as solvent, reacting 2,6-dichloropyridine used as a raw material with active metal under the action of an initiator to obtain a Grignard reagent; and cooling, then introducing excessive dry carbon dioxide gas, and acidifying to obtain the 2,6-dipicolinic acid. According to the invention, the cheap 2,6-dichloropyridine is used as the raw material, so the cost is low; and the synthesis process route is simple and easy to control, and can easily implement industrial production.
Co(ii), a catalyst for selective conversion of phenyl rings to carboxylic acid groups
Sinha, Shashi Bhushan,Campos, Jess,Brudvig, Gary W.,Crabtree, Robert H.
, p. 49395 - 49399 (2014/12/10)
An inexpensive protocol for the conversion of -C6H4R into -COOH groups using Co(ii)-Oxone mixture as the catalytic system is described. A series of substrates containing substituted and non-substituted phenyl groups could be selectively converted into carboxylic acids. Initial mechanistic data have been provided.
Amino-acid templated assembly of sucrose-derived macrocycles
Lewandowski, Bartosz,Jarosz, Slawomir
scheme or table, p. 2532 - 2535 (2010/07/20)
C2-Symmetrical chiral macrocyles containing two sucrose units were prepared by an amino acid templated macrocyclization reaction between appropriate sucrose-based linear precursors and ethylenediamine.
