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Cas Database

64-19-7

64-19-7

Identification

  • Product Name:Acetic acid glacial

  • CAS Number: 64-19-7

  • EINECS:200-580-7

  • Molecular Weight:60.0526

  • Molecular Formula: C2H4O2

  • HS Code:29152100

  • Mol File:64-19-7.mol

Synonyms:Acetic acid, diluted;Acetic acid, aqueous solution;Ethanoic acid;Ethanoic acid monomer;Ethylic acid;Glacial acetic acid;Methanecarboxylic acid;Vinegar acid;Glacial acetic acid (JP14);Acetic acid;

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Safety information and MSDS view more

  • Pictogram(s):CorrosiveC,IrritantXi

  • Hazard Codes: C:Corrosive;

  • Signal Word:Danger

  • Hazard Statement:H226 Flammable liquid and vapourH314 Causes severe skin burns and eye damage

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled Fresh air, rest. Half-upright position. Refer immediately for medical attention. In case of skin contact Remove contaminated clothes. Rinse and then wash skin with water and soap. Rinse skin with plenty of water or shower for at least 15 minutes. Refer immediately for medical attention. In case of eye contact Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention. If swallowed Rinse mouth. Do NOT induce vomiting. If within a few minutes after ingestion, one small glass of water may be given to drink. Refer immediately for medical attention. Breathing of vapors causes coughing, chest pain, and irritation of nose and throat; may cause nausea andvomiting. Contact with skin and eye causes burns. (USCG, 1999)Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution. (ERG, 2016) Garlic contains many sulfhydryl compounds that act as antioxidants. However, the role of nitric oxide (NO) in inflammation is controversial. The aim of the present study is to investigate the possible protective effect of garlic against acetic acid-induced ulcerative colitis in rats, as well as the probable modulatory effect of L-arginine (NO precursor) on garlic activity. Intra-rectal inoculation of rats with 4% acetic acid for 3 consecutive days caused a significant increase in the colon weight and marked decrease in the colon length. In addition, acetic acid induced a significant increase in serum levels of nitrate as well as colonic tissue content of malondialdehyde (MDA). Moreover, colonic tissue contents of glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT) were markedly reduced. On the other hand, pre-treatment of rats with garlic (0.25 g/kgbwt, orally) for 4 consecutive weeks and 3 days during induction of colitis significantly reduced the increase in the colon weight induced by acetic acid and ameliorated alterations in oxidant and antioxidant parameters. Interestingly, oral co-administration of garlic (0.25 g/kgbwt) and L-arginine (625 mg/kgbwt) for the same period of garlic administration mitigated the changes in both colon weight and length induced by acetic acid and increased garlic effect on colon tissue contents of MDA and GSH. In conclusion, L-arginine can augment the protective effect of garlic against ulcerative colitis; an effect that might be mainly attributed to its NO donating property resulting in enhancement of garlic antioxidant effect...

  • Fire-fighting measures: Suitable extinguishing media Use water spray, dry chemical, "alcohol resistant" foam, or carbon dioxide. Use water to keep fire-exposed containers cool. Special Hazards of Combustion Products: Irritating vapor generated when heated. (USCG, 1999)Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form. (ERG, 2016)Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. (ERG, 2016) Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Remove all ignition sources. Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Cautiously neutralize spilled liquid with sodium carbonate only under the responsibility of an expert. Collect leaking liquid in sealable containers. Cautiously neutralize spilled liquid with sodium carbonate only under the responsibility of an expert. Wash away remainder with plenty of water (extra personal protection: chemical protection suit including self-contained breathing apparatus).

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Fireproof. Separated from food and feedstuffs, strong oxidants, strong acids and strong bases. Store only in original container. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access.Store in a dry, well-ventilated place. Separate from oxidizing materials and alkaline substances.

  • Exposure controls/personal protection:Occupational Exposure limit valuesRecommended Exposure Limit: 10-hour Time-Weighted Average: 10 ppm (25 mg/cu m).Recommended Exposure Limit: 15-minute Short-Term Exposure Limit: 15 ppm (37 mg/cu m).Biological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

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Relevant articles and documentsAll total 1910 Articles be found

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Cave

, p. 1853 (1953)

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Neogi,Chowdhuri

, p. 701 (1916)

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DECOMPOSITION OF PERACETIC ACID CATALYZED BY VANADIUM COMPLEXES

Makarov, A. P.,Gekhman, A. E.,Polotnyuk, O. Ya.,Moiseev, I. I.

, p. 1749 - 1752 (1985)

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New insight on an old reaction - The aqueous hydrolysis of acetic anhydride

Wiseman, Floyd Landis

, p. 1105 - 1111 (2012)

Studies have shown that aqueous reactions generating a change in pH can be accurately monitored using a fast-response pH electrode. This technique has been successfully applied in this work to the aqueous hydrolysis of acetic anhydride, which is a reaction that has been studied using a variety of techniques for nearly one hundred years. Many of these techniques involve elaborate equipment and sophisticated analyses, making the pH technique an attractive alternative. Studies here have focused on the temperature effects of the simple hydrolysis and acetate-catalyzed hydrolysis reactions. Data analyses suggest the notion that if simple hydrolysis occurs by a two-step mechanism, it does so only at low temperatures, whereas acetate-catalyzed hydrolysis occurs almost assuredly by a single step mechanism. Results of this work yield the following values for the activation parameters for simple hydrolysis (subscripted with a "w") and acetate-catalyzed hydrolysis (subscripted with an "a") at atmospheric pressure: ΔHw?=39.90. 7kJ×mol-1,ΔSw?=-227(2)J×K-1×mol-1, ΔHa?=49.7(0.3)kJ×mol-1 and ΔS?a=-1571J×K- 1×mol-1. Implications of these results are discussed in this article. Copyright

Peroxy Acid Oxidations. II. A Kinetic and Mechanistic Study of Oxidation of α-Diketones

Panda, Radhasyam,Panigrahi, Akhil Krishna,Patnaik, Chakrapani,Sahu, Sabita Kumari,Mahapatra, Sabita Kumari

, p. 1363 - 1368 (1988)

The kinetics of Baeyer-Villiger oxidation of biacetyl and benzil by peroxomonophosphoric acid and peroxomonosulfuric acid have been studied in different pH ranges at 308 K.The reactions are second order; first order each in peroxy acid and in diketone concentrations at constant pH.The oxidation rate is strongly pH-dependent; the rate increases with increase in pH.From the pH-rate data the reactivity of different peroxo species, in the oxidation, has been determined.A mechanism consistent with rate-detemining nucleophilic attack of peroxo species on carbonyl carbon of the diketone molecule has been proposed.Acetic acid and benzoic acid are respectively found to be the products of oxidation of biacetyl and benzil.

Synthesis of Pd-Pt Ultrathin Assembled Nanosheets as Highly Efficient Electrocatalysts for Ethanol Oxidation

Choi, Sang-Il,Han, Yeji,Hong, Jong Wook,Kim, Jeonghyeon,Lee, Su-Un

, (2020)

Control over composition and morphology of nanocrystals (NCs) is significant to develop advanced catalysts applicable to polymer electrolyte membrane fuel cells and further overcome the performance limitations. Here, we present a facile synthesis of Pd?Pt alloy ultrathin assembled nanosheets (UANs) by regulating the growth behavior of Pd?Pt nanostructures. Iodide ions supplied from KI play as capping agents for the {111} plane to promote 2-dimensional (2D) growth of Pd and Pt, and the optimal concentrations of cetyltrimethylammonium chloride and ascorbic acid result in the generation of Pd?Pt alloy UANs in high yield. The prepared Pd?Pt alloy UANs exhibited the remarkable enhancement of the catalytic activity and stability toward ethanol oxidation reaction compared to irregular-shaped Pd?Pt alloy NCs, commercial Pd/C, and commercial Pt/C. Our results confirm that the Pd?Pt alloy composition and ultrathin 2D morphology offer high accessible active sites and favorable electronic structure for enhancing electrocatalytic activity.

Kinetics of formation of peroxyacetic acid

Dul'neva,Moskvin

, p. 1125 - 1130 (2005)

The kinetics of the reaction of acetic acid with hydrogen peroxide, leading to peroxyacetic acid, were studied at various molar reactant ratios (AcOH-H2O2 from 6 : 1 to 1 : 6) at 20, 40, and 60°C and sulfuric acid (catalyst) concentrations of 0 to 9 wt %. The reaction is reversible, and the equilibrium constant decreases as the temperature rises: K = 2.10 (20°C), 1.46 (40°C), 1.07 (60°C); Δr H 0 = - 13.7±0.1 kJ mol-1, Δr S = -40.5±0.4 J mol-1 K-1. The maximal equilibrium concentration of peroxyacetic acid (2.3 M) is attained at 20°C and a molar AcOH-to-H2O2 ratio of 2.5 : 1. The rate constants of both forward and reverse reactions increase with increase in sulfuric acid concentration from 0 to 5 wt %. Further raising the catalyst concentration does not affect the reaction rate. The reaction mechanism is discussed. 2005 Pleiades Publishing, Inc.

Rapid Aqueous Synthesis of Large-Size and Edge/Defect-Rich Porous Pd and Pd-Alloyed Nanomesh for Electrocatalytic Ethanol Oxidation

Teng, Yuxiang,Guo, Ke,Fan, Dongping,Guo, Hongyou,Han, Min,Xu, Dongdong,Bao, Jianchun

, p. 11175 - 11182 (2021)

In this work, a facile aqueous synthesis strategy was used (complete in 5 min at room temperature) to produce large-size Pd, PdCu, and PdPtCu nanomeshes without additional organic ligands or solvent and the volume restriction of reaction solution. The obtained metallic nanomeshes possess graphene-like morphology and a large size of dozens of microns. Abundant edges (coordinatively unsaturated sites, steps, and corners), defects (twins), and mesopores are seen in the metallic ultrathin structures. The formation mechanism for porous Pd nanomeshes disclosed that they undergo oriented attachment growth along the ?111? direction. Owing to structural and compositional advantages, PdCu porous nanomeshes with certain elemental ratios (e. g., Pd87Cu13) presented enhanced electrocatalytic performance (larger mass activity, better CO tolerance and stability) toward ethanol oxidation.

A high-throughput pH-based colorimetric assay: application focus on alpha/beta hydrolases

Paye, Mariétou F.,Rose, Harrison B.,Robbins, John M.,Yunda, Diana A.,Cho, Seonggeon,Bommarius, Andreas S.

, p. 80 - 90 (2018)

Research involving α/β hydrolases, including α-amino acid ester hydrolase and cocaine esterase, has been limited by the lack of an online high throughput screening assay. The development of a high throughput screening assay capable of detecting α/β hydrolase activity toward specific substrates and/or chemical reactions (e.g., hydrolysis in lieu of amidase activity and/or synthesis instead of thioesterase activity) is of interest in a broad set of scientific questions and applications. Here we present a general framework for pH-based colorimetric assays, as well as the mathematical considerations necessary to estimate de novo the experimental response required to assign a ‘hit’ or a ‘miss,’ in the absence of experimental standard curves. This combination is valuable for screening the hydrolysis and synthesis activity of α/β hydrolases on a variety of substrates, and produces data comparable to the current standard technique involving High Performance Liquid Chromatography (HPLC). In contrast to HPLC, this assay enables screening experiments to be performed with greater efficiency.

Polyoxometalate-Modified Fabrics: New Catalytic Materials for Low-Temperature Aerobic Oxidation

Xu, Ling,Boring, Eric,Hill, Craig L.

, p. 394 - 405 (2000)

The polyoxometalate H5PV2Mo10O40 (1) is deposited on cotton cloth, polyacrylic fiber, nylon fiber, carbon powder (Ambersorb 572), and the Japanese "self-deodorizing" fabric Smoklin by immersion of these materials in aqueous solutions of 1 followed by evaporation of the water. DRIFT spectra and chemical reactivity indicate that 1 is not damaged during deposition on the materials. More significantly, they catalyze O2-based oxidations of two representative and common toxics in air, acetaldehyde and 1-propanethiol, in addition to a representative thioether, tetrahydrothiophene. These aerobic oxidations proceed heterogeneously with the substrates in the liquid phase and under unusually mild conditions (mostly ambient temperature and pressure). One representative reaction, CH3CHO+O2→CH3COOH, catalyzed by several 1-fabric materials is examined in some detail. Kinetics, radical scavenging, and other experiments are consistent with the 1-fabric functioning primarily as a radical chain initiator. Surface area measurements and scanning electron microscopy of two representative materials, 1-polyacrylic and 1-Smoklin, before and after deposition of 1 and after catalysis indicate that the fibers are not demonstrably altered by deposition of 1, and that the 1-fabric catalysts are not significantly deactivated by use. In all cases, the surface areas are 2/g by BET N2 adsorption, and the deposition morphology is clumps of 1 microcrystals covering 2 oxidations in our evaluations. In contrast, 1-Smoklin is quite acti ve for all these processes.

Kinetic studies on the oxidation of iodide by peroxyacetic acid

Awad, Mohamed Ismail,Oritani, Tadato,Ohsaka, Takeo

, p. 253 - 256 (2003)

The kinetics of the oxidation of iodide by peroxyacetic acid (PAA) in aqueous media in the presence and absence of the heptamolybdate has been studied by a high time resolution spectrophotometric stopped-flow method. The time-dependent concentration of the liberated iodine was monitored by the change in absorbance at 352 nm. The effect of ammonium heptamolybdate as well as pH on the rate of the reaction was also studied and it was found that the rate of the reaction is independent of pH and molybdate concentration under the examined conditions. The results obtained show that the rate law of the reaction can be expressed as rate=k[PAA][I-] with a value of k=4.22×102 (mole/l)-1 s-1 at pH 3.5-5.4 and 25°C.

Substrate Specificity and Leaving Group Effect in Ester Cleavage by Metal Complexes of an Oximate Nucleophile

Lugo-González, José Carlos,Gómez-Tagle, Paola,Huang, Xiaomin,M. Del Campo, Jorge,Yatsimirsky, Anatoly K.

, p. 2060 - 2069 (2017)

Deprotonated zinc(II) and cadmium(II) complexes of a tridentate oxime nucleophile (1, OxH) show a very high reactivity, breaking by 2-3 orders of magnitude the previously established limiting reactivity of oximate nucleophiles in the cleavage of substituted phenyl acetates and phosphate triesters, but are unreactive with p-nitrophenyl phosphate di- and monoesters. With reactive substrates, these complexes operate as true catalysts through an acylation-deacylation mechanism. Detailed speciation and kinetic studies in a wide pH interval allowed us to establish as catalytically active forms [Cd(Ox)]+, [Zn(Ox)(OH)], and [Zn(Ox)(OH)2]? complexes. The formation of an unusual and most reactive zinc(II) oximatodihydroxo complex was confirmed by electrospray ionization mass spectrometry data and supported by density functional theory calculations, which also supported the previously noticed fact that the coordinated water in [Zn(OxH)(H2O)2]2+ deprotonates before the oxime. Analysis of the leaving group effect on the cleavage of phenyl acetates shows that the rate-determining step in the reaction with the free oximate anion is the nucleophilic attack, while with both zinc(II) and cadmium(II) oximate complexes, it changes to the expulsion of the leaving phenolate anion. The major new features of these complexes are (1) a very high esterolytic activity surpassing that of enzyme hydrolysis of aryl acetate esters and (2) an increased reactivity of coordinated oxime compared to free oxime in phosphate triester cleavage, contrary to the previously observed inhibitory effect of oxime coordination with these substrates.

Activity, recyclability, and stability of lipases immobilized on oil-filled spherical silica nanoparticles with different silica shell structures

Kuwahara, Yasutaka,Yamanishi, Takato,Kamegawa, Takashi,Mori, Kohsuke,Yamashita, Hiromi

, p. 2527 - 2536 (2013)

Candida antarctica lipaseA was immobilized on spherical silica nanoparticles with oil-filled core and oil-induced mesoporous silica shell with different silica shell structures. The immobilization of enzymes was achieved by directly adding enzymes to the oil-in-water emulsion system under ambient synthesis conditions, and the silica shell structure was controlled by the addition of the cosolvent ethanol to the initial synthesis medium. Detailed structural analysis revealed the formation of oil-filled spherical silica nanoparticles with 3.4-4.2nm mesopores randomly arranged in the silica shell; the thickness and pore characteristics of these pores markedly changed with the addition of ethanol. The retention of the enzyme activity during biocatalysis was significantly affected by the structural properties of the silica shells, and it was found that a thick and dense silica shell is essential to afford an active, recyclable, and stable biocatalyst. Furthermore, the oil encapsulated within the core cavity was found to play an important role in achieving a high catalytic efficiency. Trapped oil: Candida antarctica lipaseA is immobilized on oil-filled spherical silica nanoparticles with different silica shell structures through an anionic surfactant-induced self-assembly approach (see scheme) with ethanol as a cosolvent. The entrapped enzymes mostly retain their activities and exhibit recyclability and thermal and chemical stability, depending on the thickness and pore characteristics of the silica shells. TEOS=Tetraethoxyorthosilicate, APTES=3-aminopropyl triethoxysilane.

Exceptionally stable Rh-based molecular catalyst heterogenized on a cationically charged covalent triazine framework support for efficient methanol carbonylation

Park, Kwangho,Lim, Sangyup,Baik, Joon Hyun,Kim, Honggon,Jung, Kwang-Deog,Yoon, Sungho

, p. 2894 - 2900 (2018)

Direct carbonylation of methanol into methyl acetate and acetic acid using Rh-based heterogeneous catalysts is of great interest due to their effective levels of activity and stability. Here, a Rh-based molecular catalyst heterogenized on a charged 1,3-bis(pyridyl)imidazolium-based covalent triazine framework (Rh-bpim-CTF) was synthesized and characterized to have a single-site distribution of metal molecular species throughout the support by its ligation to abundant N atom sites. Methanol carbonylation was performed using the Rh-bpim-CTF catalyst in a plug-flow reaction in the gas phase, affording a turnover frequency of up to 3693 h-1 and a productivity of 218.9 mol kg-1 h-1 for acetyl products with high stability.

Radical catalyzed debromination of bromo-alkanes by formate in aqueous solutions via a hydrogen atom transfer mechanism

Shandalov, Elisabetha,Zilbermann, Israel,Maimon, Eric,Nahmani, Yeoshua,Cohen, Haim,Adar, Eilon,Meyerstein, Dan

, p. 989 - 992 (2004)

CO2·- radicals catalyze the dehalogenation of bromo-alkanes by formate via a hydrogen atom transfer mechanism.

Critical phenomena in acetone oxidation by nitric acid

Rubtsov, Yu. I.,Kazakov,Sorokina,Manelis

, p. 2065 - 2071 (2008)

The kinetic regularities of acetone oxidation by aqueous nitric acid solutions (5.86-58.31 wt.%) were studied using a differential automatic microcalorimeter. The critical phenomena were discovered, which manifest themselves as a abrupt change in the initial heat release rate at a minor change in the temperature or acid concentration. The abrupt change in the oxidative activity of the reactant at a minor change in the system parameter was assumed to be related to changes in the structure of the solution and, as a consequence, in the solvation energy of the reactants at a certain acid/water ratio in the solution.

A Highly Efficient Copper(II) Complex catalysed Hydrolysis of Methyl Acetate at pH 7.0 and 25 deg C

Chin, Jik,Jubian, Vrej

, p. 839 - 841 (1989)

The turnover time for 2+ (1 mM) catalysed hydrolysis of methyl acetate (1 M) is 23 min at pH 7, 25 deg C.

Efficient production of acrylic acid by dehydration of lactic acid over BaSO4 with crystal defects

Lyu, Shuting,Wang, Tiefeng

, p. 10278 - 10286 (2017)

BaSO4 catalysts with different micromorphologies and crystal texture were prepared and used to investigate the structure-activity relationship in the dehydration reaction of lactic acid (LA) to acrylic acid (AA). SEM and N2 physisorption were used to study the micromorphology. XRD and photoluminescence spectra were employed to analyze the crystal texture of samples prepared with different methods and treatments. The results revealed that BaSO4 with smaller crystals and more defects had higher activity and selectivity to AA. It was likely that the crystal defects provided the active acid sites for dehydration of LA to AA, as evidenced by XPS and NH3-TPD measurements. Using ethanol as the solvent and ultrasound treatment during the preparation of BaSO4, imperfect small crystals with more defects were formed, which increased the AA selectivity to 78.8%.

Selective oxidation of ethane to acetic acid selective oxidation of ethane to acetic acid catalyzed catalyzed by by a c-scorpionate c-scorpionate iron(Ii) iron(ii) complex: Complex: A ahomogeneous vs.vs.heterogeneous comparison

Martins, Luísa M. D. R. S.,Matias, Inês A. S.,Ribeiro, Ana P. C.

, (2020)

The direct, one-pot oxidation of ethane to acetic acid was, for the first time, performed using a C-scorpionate complex anchored onto a magnetic core-shell support, the Fe3O4/TiO2/[FeCl2{κ3 -HC(pz)3}] composite. This catalytic system, where the magnetic catalyst is easily recovered and reused, is highly selective to the acetic acid synthesis. The performed green metrics calculations highlight the “greeness” of the new ethane oxidation procedure.

Single-pot ethane carboxylation catalyzed by new oxorhenium(V) complexes with N,O ligands

Kirillov, Alexander M.,Haukka, Matti,Kirillova, Marina V.,Pombeiro, Armando J. L.

, p. 1435 - 1446 (2005)

The oxorhenium(V) chelates [ReOCl-(N,O-L)(PPh3] [N,O-L = (OCH2CH2)N(CH2CH2,OH)-(CH 2COO) (2), (OCH2CH2)N(CH2COO) (CH2-COOCH3) (3)] and [ReOCl2(N,O-L)(PPh 3] [N,O-L = C5H4N(COO-2) (4) C 5H3(COOCH3-2)(COO-6) (5)] have been prepared by reaction of [ReOCl3(PPh3)2] (1), in refluxing methanol, with N,N-bis(2-hydroxy-ethyl)glycine [bicine; N(CH2CH 2OH)2(CH2COOH)], N-(2-hydroxyethyl) iminodiacetic acid [N(CH2CH2-OH)(CH2COOH) 2], picolinic acid [NC5H4(COOH-2)] or 2,6-pyridinedicarboxylic acid [NC5H3(COOH-2,6) 2], respectively, with ligand esterification in the cases of 3 and 5. All these complexes have been characterized by IR and multinuclear NMR spectroscopy, FAB+-MS, elemental and X-ray diffraction structural analyses. They act as catalysts, in a single-pot process, for the carboxylation of ethane by CO, in the presence of potassium peroxodisulfate K 2S2O8, in trifluoroacetic acid (TFA), to give propionic and acetic acids, in a remarkable yield (up to ca. 30%) and under relatively mild conditions, with some advantages over the industrial processes. The picolinate complex 4 provides the most active catalyst and the carboxylation also occurs, although much less efficiently, by the TFA solvent in the absence of CO. The selectivity can be controlled by the ethane and CO pressures, propionic acid being the dominant product for pressures about ca. 7 and 4 atm, respectively (catalyst 4), whereas lower pressures lead mainly to acetic acid in lower yields. These reactions constitute an unprecedented use of Re complexes as catalysts in alkane functionalization.

Langenbeck,Ruzicka

, p. 192 (1955)

Hydrothermal process for increasing acetic acid yield from lignocellulosic wastes

Jin, Fangming,Zheng, Junchao,Enomoto, Heiji,Moriya, Takehiko,Sato, Naohiro,Higashijima, Hisao

, p. 504 - 505 (2002)

To increase the acetic acid yield in a wet oxidation of lignocellulosic wastes, a new two-step reaction process is proposed. The first step produces 5-hydroxymethyl-2-furaldehyde (HMF) and 2-furaldehyde (2-FA) by dehydration of monosaccharides which are f

Effect of ammonium perfluorooctanoate on acetylcholinesterase activity and inhibition using MALDI-FTICRMS

Cai, Tingting,Zhang, Li,Wang, Rong,Liang, Chen,Zhang, Yurong,Guo, Yinlong

, p. 80 - 83 (2013)

Ammonium perfluorooctanoate (APFO) is a commercially important compound, but its harm to people's health has raised widespread concern. In the past, the investigations into APFO and its degradation product (perfluorooctanoic acid, PFOA) were all about their effect on indicator compounds in animals and enzyme activities. Here, we provided a new suggestion to investigate the influence of APFO and PFOA. Acetylcholinesterase (AChE) was chosen as research subject to reflect the effect of external perfluorochemicals. We applied matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry (MALDI-FTICRMS) to detect the activity of AChE rapidly and accurately. On this basis, not only AChE activity but also AChE inhibition was studied carefully. The presence of APFO and PFOA showed obvious increase of AChE activity. Moreover, addition of both APFO and PFOA had enhanced AChE inhibition from organophosphorous (OP) pesticide (irreversible inhibitor). Otherwise, the participation of APFO and PFOA had not increased AChE inhibitions from reversible inhibitor galantamine. These results might provide new insights into the effect of APFO and encourage the deep understanding about effect of APFO on human being.

Adsorption and catalytic properties of the inner nanospace of a gigantic ring-shaped polyoxometalate cluster

Noro, Shin-Ichiro,Tsunashima, Ryo,Kamiya, Yuichi,Uemura, Kazuhiro,Kita, Hidetoshi,Cronin, Leroy,Akutagawa, Tomoyuki,Nakamura, Takayoshi

, p. 8703 - 8706 (2009)

Functional inner space: A gigantic ringshaped {Mo154} polyoxometalate cluster anion can be stabilized by encapsulation in dimethyldioctadecylammonium (DODA) cations. Its inner nanospace enables adsorption of gases and vapors, and it acts as a water-tolerant solid acid catalyst (see scheme).

Oxidative decarboxylation of levulinic acid by cupric oxides

Gong, Yan,Lin, Lu,Shi, Jianbin,Liu, Shijie

, p. 7946 - 7960 (2010)

In this paper, cupric oxides was found to effectively oxidize levulinic acid (LA) and lead to the decarboxylation of levulinic acid to 2-butanone. The effects of cupric oxide dosage, reaction time and initial pH value were investigated in batch experiments and a plausible mechanism was proposed. The results showed that LA decarboxylation over cupric oxides at around 300 °C under acidic conditions produced the highest yield of butanone (67.5%). In order to elucidate the catalytic activity of cupric oxides, XRD, AFM, XPS and H 2-TPR techniques was applied to examine their molecular surfaces and their effects on the reaction process.

Amavadin and other vanadium complexes as remarkably efficient catalysts for one-pot conversion of ethane to propionic and acetic acids

Kirillova, Marina V.,Kuznetsov, Maxim L.,Da Silva, Jose A. L.,Guedes Da Silva, Maria Fatima C.,Frausto Da Silva, Joao J. R.,Pombeiro, Armando J. L.

, p. 1828 - 1842 (2008)

Synthetic amavadin Ca[V{ON[CH(CH3)COO]2}2] and its models Ca[V{ON(CH2COO)2}2] and [VO{N(CH2CH2O}3)], in the presence of K 2S2O8 in trifluoroacetic acid (TFA), exhibit remarkable catalytic activity for the one-pot carboxylation of ethane to propionic and acetic acids with the former as the main product (overall yields up to 93%, catalyst turnover numbers (TONs) up to 2.0×104). The simpler V complexes [VO(CF3SO3)2], [VO(acac)2] and VOSO4 are less active. The effects of various factors, namely, C2H6 and CO pressures, time, temperature, and amounts of catalyst, TFA and K2S2O 8, have been investigated, and this allowed optimisation of the process and control of selectivity. 13C-labelling experiments indicated that the formation of acetic acid follows two pathways, the dominant one via oxidation of ethane with preservation of the C-C bond, and the other via rupture of this bond and carbonylation of the methyl group by CO; the C-C bond is retained in the formation of propionic acid upon carbonylation of ethane. The reactions proceed via both C- and Ocentred radicals, as shown by experiments with radical traps. On the basis of detailed DFT calculations, plausible reaction mechanisms are discussed. The carboxylation of ethane in the presence of CO follows the sequential formation of C2H5 ., C2H5CO., C2H 5COO. and C2H5COOH. The C 2H5COO. radical is easily formed on reaction of C2H5CO. with a peroxo V catalyst via a V{η-OOC(O)C2H5) intermediate. In the absence of CO, carboxylation proceeds by reaction of C2H5. with TFA. For the oxidation of ethane to acetic acid, either with preservation or cleavage of the C-C bond, metal-assisted and purely organic pathways are also proposed and discussed.

Single-pot conversion of methane into acetic acid in the absence of CO and with vanadium catalysts such as amavadine

Reis, Patricia M.,Silva, Jose A. L.,Palavra, Antonio F.,Frausto da Silva, Joao J. R.,Kitamura, Tsugio,Fujiwara, Yuzo,Pombeiro, Armando J. L.

, p. 821 - 823 (2003)

Although its biological function is still unknown, the naturally occurring vanadium complex amavadine may be suitable for industrial applications: This compound (as well as other VIV and VV complexes with N,O and O,O ligands) are shown to act as catalysts for the direct conversion of methane into acetic acid, without requiring CO, under very mild conditions and in high yields (see scheme).

A facile post-synthetic modification of ordered mesoporous carbon to get efficient catalysts for the formation of acetins

Goscianska, Joanna,Malaika, Anna

, p. 84 - 93 (2020)

Highly active and stable solid acid catalysts based on ordered mesoporous carbons were synthesized via hard template method and further functionalization with sulfonic (SO3H) groups. Two post-synthetic modification strategies were applied. In the first one, the pristine carbon was modified with concentrated sulfuric acid. The second approach included the reaction of carbon with aryl diazonium cation generated in situ from sulfanilic acid. The morphology, structure, composition, and surface functionalities of the resulting carbons were determined by scanning and transmission electron microscopy, X-ray diffraction, thermogravimetric analysis, N2 adsorption-desorption measurement, elemental analysis, potentiometric titration, X-ray photoelectron spectroscopy and FT-IR method. The obtained samples were further tested in acetylation of glycerol with acetic acid under various conditions, and were found to efficiently produce acetins, valuable fuel additives. An excellent catalytic activity was shown especially by the SO3H-bearing mesoporous carbon prepared by a facile method with the use of 4-benzenediazonium sulfonate under ambient conditions. Furthermore, very good recycling properties of this catalyst was demonstrated by four consecutive runs. It is supposed that acidic catalytic activity of the synthesized materials can be further extended to other acid-catalyzed reactions.

Reactor kinetics studies via process raman spectroscopy, multivariate chemometrics, and kinetics modeling

Assirelli, Melissa,Xu, Weiyin,Chew, Wee

, p. 610 - 621 (2011)

The deployment of in situ analytics for monitoring chemical reactions in process chemistry development and scale-up is facilitated by advanced instrumentation such as Raman spectrometry. Furthermore, greater process understanding can be engendered by coupling in situ Raman data with multivariate chemometrics analyses and kinetics modeling. Such information is important for devising science-based process control strategies along the concept of quality by design (QbD) initiated through the U.S. FDA process analytical technology (PAT) framework. A series of experiments using varied glass reactors, stirring speeds, and isothermal reaction temperatures were designed with acetic anhydride hydrolysis as the model reaction to successfully demonstrate the efficacy of combining in situ Raman spectroscopy, multivariate analyses, and kinetics modeling. Two different Raman measurement methods, using immersion and noncontact probe optics, were tested through a process Raman spectrometer with multiplexing capability. Information-theoretic multivariate chemometrics were applied to elicit pure component spectra and transient concentrations of chemical species, and two differential-algebraic equations modeling approaches were adopted for elucidating chemical and dissolution kinetics information. The variations in reactor vessel type and sizes, stirring speeds, Raman measurements, and kinetics models were compared in this study.

Willmarth, W. K.,Kapauan, A. F.

, p. 1308 - 1311 (1956)

Effect of Pd loading and precursor on the catalytic performance of Pd/WO3-ZrO2 catalysts for selective oxidation of ethylene

Wang, Lixia,Xu, Shuliang,Chu, Wenling,Yang, Weishen

, p. 163 - 166 (2010)

The structure and properties of Pd/WO3-ZrO2 (W/Zr = 0.2) catalysts with different Pd loadings and precursors were investigated. The results indicate that Pd/WO3-ZrO2 prepared from a PdCl2 precursor was optimum for high activity and selectivity. Moreover, ethylene conversion increased with the Pd loading. The structure and nature of the catalysts were characterized using X-ray diffraction, BET N2 adsorption, H2 temperature-programmed reduction and H2 pulse adsorption techniques. The results reveal that the higher catalytic performance of Pd/WO3-ZrO2 prepared from PdCl2 could be related to the formation of polytungstate species and the existence of well-dispersed Pd particles.

Temperature Dependence of Collisional Energy Transfer in Ethyl Acetate

Brown, Trevor C.,Taylor, John A.,King, Keith D.,Gilbert, Robert G.

, p. 5214 - 5219 (1983)

Results are reported for the temperature and pressure dependence of the rate coefficient for the thermal unimolecular decomposition of ethyl acetate, obtained by using very low-pressure pyrolysis (VLPP) over the range 800-1150 K, both under conditions where only gas/wall collision occur and also (at 837 K) dilute in a number of bath gases (He, Ar, Ne, Kr, N2, and C2H4).Solution of the appropriate reaction-diffusion master equation yields from these data both the extrapolated high-pressure rate coefficient (1012.7 exp(-201.5 kJ mol-1/RT) s-1) and the average downward collisional energy transfer, down>.The down> values are compared with those obtained for the same collision partners at ca. 340 K using multiple-photon dissociation (mpd).It is found that, for mon- and diatomic bath gases, down> is approximately proportional to T-(0.1-0.3) (for He, Ne) and to T-(0.3-0.5) (for Ar, Kr, N2).The combination of thermal and mpd techniques used here is generally applicable to obataining collisional energy-transfer data of highly vibrationally excited molecules over a wide range of temperatures and collision partners.

Conversion of Formaldehyde to Acetic Acid. Formic Acid as a Stoichiometric CO Substitute

Kaplan, Leonard

, p. 5376 - 5377 (1985)

-

-

Wagner

, p. 310 (1891)

-

Dissociative nucleophilic substitution of η2-olefin complexes via a novel η2-vinyl cation inTermediate

Chen, Huiyuan,Harman, W. Dean

, p. 5672 - 5683 (1996)

A series of η2-[Os(NH3)5(vinyl ether)]2+ complexes have been prepared by three independent methods that involve direct coordination of a vinyl ether, alcohol addition to an η2-alkyne complex, or nucleophilic substitution of an η2-vinyl ether species. In the presence of an acid catalyst, the vinyl ether ligand undergoes a novel acid-catalyzed substitution reaction at the α-carbon with a broad range of nucleophiles that includes alcohols, amines, carboxylates, hydrides, silylated enols, nitriles, phosphines, and dialkyl sulfides. These reactions appear to proceed through an elimination-addition process where the first step is loss of an alcohol to form an η2-vinyl cation intermediate. In cases where the α-carbon bears an alkyl group, an η2-vinyl cation species can be isolated and characterized. For example, protonation of [Os(NH3)5(η2-2-methoxypropene)]2+ (3) in neat HOTf allows the characterization of the substitution reaction intermediate η2-[Os(NH3)5(C3H5)]3+ (32), formally a metallocyclopropene that behaves chemically like a vinyl cation. In contrast, when the α-carbon of the vinyl ether bears a hydrogen such as with [Os(NH3)5(η2-ethoxyethene)]2+ (1), the hypothetical vinyl cation intermediate, in absence of a suitable nucleophile, undergoes an intramolecular 1,2-hydrogen shift to yield the Fischer carbyne [(NH3)5Os≡CCH3]3+ (33). Examples of nucleophilic substitution reactions for other types of η2-[Os(NH3)5(olefin)](n+) complexes are also demonstrated.

Oxidations by the system 'hydrogen peroxide-[Mn2L2O3][PF6] 2 (L=1,4,7-trimethyl-1,4,7-triazacyclononane)-carboxylic acid'. Part 10: Co-catalytic effect of different carboxylic acids in the oxidation of cyclohexane, cyclohexanol, and acetone

Shul'pin, Georgiy B.,Matthes, Marianne G.,Romakh, Vladimir B.,Barbosa, Marília I.F.,Aoyagi, Jonatas L.T.,Mandelli, Dalmo

, p. 2143 - 2152 (2008)

Hydrogen peroxide oxidation of cyclohexane in acetonitrile solution catalyzed by the dinuclear manganese(IV) complex [LMn(O)3MnL](PF6)2 (L=1,4,7-trimethyl-1,4,7-triazacyclononane, TMTACN) at 25 °C in the presence of a carboxylic acid affords cyclohexyl hydroperoxide as well as cyclohexanone and cyclohexanol. A kinetic study of the reactions with participation of three acids (acetic acid, oxalic acid, and pyrazine-2,3-dicarboxylic acid, 2,3-PDCA) led to the following general scheme. In the first stage, the catalyst precursor forms an adduct. The equilibrium constants K1 calculated for acetic acid, oxalic acid, and 2,3-PDCA were 127±8, (7±2)×104, and 1250±50 M-1, respectively. The same kinetic scheme was applied for the cyclohexanol oxidation catalyzed by the complex in the presence of oxalic acid. The oxidation of cyclohexane in water solution using oxalic acid as a co-catalyst gave cyclohexanol and cyclohexanone, which were rapidly transformed into a mixture of over-oxidation products. In the oxidation of cyclohexanol to cyclohexanone, varying the concentrations of the reactants and the reaction time we were able to find optimal conditions and to obtain the cyclohexanone in 94% yield based on the starting cyclohexanol. Oxidation of acetone to acetic acid by the system containing oxalic acid was also studied.

Dioxygen activation at room temperature during controllable and highly efficient acetaldehyde-to-acetic acid oxidation using a simple iron(III)-acetonitrile complex

Li, Renhong,Kobayashi, Hisayoshi,Yan, Xiaoqing,Fan, Jie

, p. 140 - 146 (2014)

We show that highly efficient acetaldehyde-to-acetic acid oxidation is achieved in a diluted FeCl3-acetonitrile solution (5-100 μM), which proceeds rather rapidly and follows the enzymatic-like Michaelis-Menten kinetics. Interestingly, by adjusting the concentration of FeCl3, we are able to accelerate or shut down the oxidation process conveniently. Based on the catalytic results, spectroscopic evidences and successive DFT calculations, a reactant-initiated, putative mononuclear non-heme iron-oxygen complex, [FeCl(MeCN)4(O)]2+, is proposed as the active oxidizing species to conduct the room temperature reaction with relatively high TOF values (~1.2 s-1). Finally, the putative iron-oxygen complexes are employed to the selective oxidation of benzyl alcohol under ambient conditions.

Solar-Powered Organic Semiconductor–Bacteria Biohybrids for CO2 Reduction into Acetic Acid

Gai, Panpan,Li, Feng,Liu, Libing,Lv, Fengting,Qi, Ruilian,Wang, Shu,Yu, Wen,Zhao, Hao

, p. 7224 - 7229 (2020)

An organic semiconductor–bacteria biohybrid photosynthetic system is used to efficiently realize CO2 reduction to produce acetic acid with the non-photosynthetic bacteria Moorella thermoacetica. Perylene diimide derivative (PDI) and poly(fluorene-co-phenylene) (PFP) were coated on the bacteria surface as photosensitizers to form a p-n heterojunction (PFP/PDI) layer, affording higher hole/electron separation efficiency. The π-conjugated semiconductors possess excellent light-harvesting ability and biocompatibility, and the cationic side chains of organic semiconductors could intercalate into cell membranes, ensuring efficient electron transfer to bacteria. Moorella thermoacetica can thus harvest photoexcited electrons from the PFP/PDI heterojunction, driving the Wood–Ljungdahl pathway to synthesize acetic acid from CO2 under illumination. The efficiency of this organic biohybrid is about 1.6 %, which is comparable to those of reported inorganic biohybrid systems.

Structure and characterization of amidase from Rhodococcus sp. N-771: Insight into the molecular mechanism of substrate recognition

Ohtaki, Akashi,Murata, Kensuke,Sato, Yuichi,Noguchi, Keiichi,Miyatake, Hideyuki,Dohmae, Naoshi,Yamada, Kazuhiro,Yohda, Masafumi,Odaka, Masfumi

, p. 184 - 192 (2010)

In this study, we have structurally characterized the amidase of a nitrile-degrading bacterium, Rhodococcus sp. N-771 (RhAmidase). RhAmidase belongs to amidase signature (AS) family, a group of amidase families, and is responsible for the degradation of amides produced from nitriles by nitrile hydratase. Recombinant RhAmidase exists as a dimer of about 107?kDa. RhAmidase can hydrolyze acetamide, propionamide, acrylamide and benzamide with kcat/Km values of 1.14 ± 0.23?mM- 1s- 1, 4.54 ± 0.09?mM- 1s- 1, 0.087 ± 0.02?mM- 1s- 1 and 153.5 ± 7.1?mM- 1s- 1, respectively. The crystal structures of RhAmidase and its inactive mutant complex with benzamide (S195A/benzamide) were determined at resolutions of 2.17?A? and 2.32?A?, respectively. RhAmidase has three domains: an N-terminal α-helical domain, a small domain and a large domain. The N-terminal α-helical domain is not found in other AS family enzymes. This domain is involved in the formation of the dimer structure and, together with the small domain, forms a narrow substrate-binding tunnel. The large domain showed high structural similarities to those of other AS family enzymes. The Ser-cis Ser-Lys catalytic triad is located in the large domain. But the substrate-binding pocket of RhAmidase is relatively narrow, due to the presence of the helix α13 in the small domain. The hydrophobic residues from the small domain are involved in recognizing the substrate. The small domain likely participates in substrate recognition and is related to the difference of substrate specificities among the AS family amidases.

A highly efficient catalyst precursor for ethanoic acid production: [RhCl(CO)(PEt3)2]; X-ray crystal and molecular structure of carbonyldiiodo(methyl)bis(triethylphosphine)rhodium(III)

Rankin, Joanne,Poole, Andrew D.,Benyei, Attila C.,Cole-Hamilton, David J.

, p. 1835 - 1836 (1997)

Under mild conditions, [RhI(CO)(PEt3)2], is more active for the carbonylation of methanol to ethanoic acid than [Rh(CO)2I2]-, which is widely used industrially; intermediates in the catalytic cycle have been identified and characterised.

Coenzyme Models. 33. Evidence for Retro-acyloin Condensation as Catalyzed by Thiazolium Ion and Cationic Micelle. Oxidative Trapping of the "Active Aldehyde" Intermediates by Flavin

Shinkai, Seiji,Hara, Youichiro,Manabe, Osamu

, p. 770 - 774 (1983)

N-Hexadecylthiazolium bromide (HxdT) in the CTAB micelle, which is known as an excellent catalytic system for acyloin condensation of aldehydes, catalyzes the reverse reaction (i.e., retro-acyloin condensation) to give aldehydes from α-ketols via the active aldehyde intermediates.The existence of the novel, HxdT-mediated process was proposed on the basis of an experimental discovery that flavin (3-methyltetra-O-acetylriboflavin: MeFl), which is capable of oxidatively trapping the active aldehyde intermediates, is reduced by α-ketols such as acetoin and 3-hydroxy-3-methyl-2-butanone in the micellized HxdT solution.It was further substantiated by detection of acetaldehyde in the final reaction mixture.Based on the diasappearance rate of the absorbance of MeFl, we spectrophotometrically estimated the rate constants for the retro-acyloin condensation.Similarly, biacetyl, the monohydrated species of which is analogous to α-ketol, afforded acetaldehyde and acetic acid in the micellized HxdT solution, the rate constant being greater by factors of 102-103 than those for α-ketols.The relevance of the retro-acyloin condensation to biological systems (e.g., the mechanism of transketolase catalysis) is discussed.

Nitrogen isotope effects on acetylcholinesterase-catalyzed hydrolysis of o-nitroacetanilide

Rao, Muralikrishna,Barlow, Paul N.,Pryor, Alton N.,Paneth, Pyotr,O'Leary, Marion H.,Quinn, Daniel M.,Phillip Huskey

, p. 11676 - 11681 (1993)

The nitrogen-15 isotope effect on V/K for Electrophorus electricus acetylcholinesterase-catalyzed hydrolysis of o-nitroacetanilide has been determined by isotope ratio mass spectrometry. The effect determined in buffered H2O (0.1 M sodium phosphate, 0.1 N NaCl, pH 7.3, 25 °C) is 15V/K = 1.0119 ± 0.0005. A small though palpable decrease of the isotope effect is observed when the reaction is run in equivalently buffered D2O (pD = 7.7), 15V/K = 1.0106 ± 0.0002. The corresponding solvent isotope effect is DV/K = 1.56 ± 0.03. The solvent isotope effect on the nitrogen isotope effect is interpreted in terms of a mechanism in which successive transition states for induced fit and for formation and decomposition of a uninegative tetrahedral intermediate contribute to rate determination of V/K. Numerical modeling allows relatively narrow limits to be placed on the isotope effects for the chemical steps. The solvent and substrate isotope effects for the formation of the tetrahedral intermediate are DK5 = 2.6-3.7 and 15k5 = 1.000-1.009, respectively. The corresponding isotope effects for the decomposition of the intermediate are Dk7 = 1.0-1.5 and 15k7′ = 15k515k7/15k6 = 1.027-1.053. The value of 15k7′ is consistent with a transition state for decomposition of the tetrahedral intermediate in which C-N bond breaking is occurring.

Photoelectrochemistry of Levulinic Acid on Undoped Platinized n-TiO2 Powders

Chum, H. L.,Ratcliff, M.,Posey, F. L.,Turner, J. A.,Nozik, A. J.

, p. 3089 - 3093 (1983)

The photoelectrochemistry of levulinic (4-oxopentanoic) acid, the major product of controlled degradation of cellulose by acids, has been investigated.Since this acid can be present in waste streams of biomass processing, we investigated the photoelectrochemical reactions of this acid on slurries composed of semiconductor/metal particles.The semiconductor investigated was platinized undoped n-TiO2, as anatase, anatase-rutile mixture, or rutile.The effects of the level of platinization, pH, acid concentration, and the semiconductor surface area were investigated.In addition to the decarboxylation reaction leading to methyl ethyl ketone, we have also observed novel cleavages of the C-C backbone leading to propionic acid, acetic acid, acetone, and acetaldehyde as major products.These lower molecular weight carboxylic acids undergo decarboxylation at the slurry diodes to ethane and methane.The organic product distribution is a complex function of the crystallographic phase of n-TiO2 and of the level of metallization of the semiconductor powder.

Rosenthal, D.,Taylor, T. I.

, p. 2684 - 2690 (1957)

Formic Acid Promotion of Transition-metal Catalysed Isomerization of Methyl Formate

Cheong, Minserk,Bae, Seong-ho,Lee, Kang B.

, p. 1557 - 1558 (1995)

MeI-HCO2H is an extremely effective promoter/solvent combination for the transition-metal catalysed conversion of methyl formate to acetic acid in the absence of initial carbon monoxide pressure.

Kinetics and Mechanism of the Acetylperoxy + HO2 Reaction

Crawford, Mary A.,Wallington, Timothy J.,Szente, Joseph J.,Maricq, M. Matti,Francisco, Joseph S.

, p. 365 - 378 (1999)

The reaction of HO2 with CH3C(O)O2 is examined using flash photolysis and FTIR smog chamber techniques. Time-resolved UV spectroscopy is used to follow the transient peroxy species. It yields reasonable concentration versus time profiles for CH3C(O)O2 and HO2, but indicates anomalously high levels of secondary CH3O2 radicals. Transient IR diode laser absorption confirms the HO2 decay rates; however, the anticipated reaction model substantially underestimates the observed decay. The model is augmented by assuming that, in analogy with formaldehyde, there exists a reaction between HO2 and acetaldehyde (the precursor for CH3C(O)O2). Consistent with this, the fitted rate for the hypothesized reaction increases with increasing initial acetaldehyde level. Relative rate measurements reveal that chlorine atoms remove more CH3CHO relative to CH2OH in air as compared to nitrogen diluent. This supports the hypothesis since, in the presence of oxygen, HO2 is formed and presents an additional acetaldehyde removal pathway. Employing the augmented model, analyses of HO2 decay traces yield a CH3C(O)O2 + HO2 rate constant of k1 = (3.9-2.3+5.0) × 10-13e(1350±250)/T cm3 s-1. Reasons are discussed for why the present rate constants are 2 - 3 times larger than previously reported. FTIR - smog chamber studies reveal the reaction to proceed via two channels to (a) peracetic acid and O2 and to (b) acetic acid and O2, with a branching fraction at 295 K that is less than half of the literature value. Time-resolved UV absorption measurements support this smaller fraction; averaged together the two methods give k1b/k1 = 0.12 ± 0.04. As part of this work, relative rate techniques are used to measure k(Cl+CH3C- (O)OH) = (2.5 ± 0.3) × 10-14 cm3 s-1and k(Cl+CH3C(O)OOH) = (4.5 ± 1.0) × 10-15 cm3 s-1 at 295 K.

Application of band-target entropy minimization to on-line raman monitoring of an organic synthesis. An example of new technology for process analytical technology

Widjaja, Effendi,Ying, Yan Tan,Garland, Marc

, p. 98 - 103 (2007)

The hydrolysis of acetic anhydride to acetic acid in water as solvent was monitored by Raman microscopy. Both static and flow-through configurations were used in the experiments, and various experimental designs, i.e., multiple-experimental runs and multiple-perturbation semibatch mode, were considered. Various spectral data preprocessing was performed and band-target entropy minimization (BTEM) was used in the spectral analysis to recover the pure-component spectra from the multicomponent data. Good and consistent spectral estimates of the solutes acetic anhydride and acetic acid were recovered. In addition, the pure-component spectrum of white-light interference was recovered. Together, these estimates permitted very good estimates of the individual time-dependent signal contributions. Taken together, the present results suggest that the combination of Raman spectroscopy and BTEM has considerable potential for organic syntheses and process analysis. The combination of Raman spectroscopy and BTEM represents another approach for reaction monitoring in process analytical technologies (PAT).

Keggin-type molybdovanadophosphoric acids loaded on ZSM-5 zeolite as a bifunctional catalyst for oxidehydration of glycerol

Suganuma, Satoshi,Hisazumi, Takuya,Taruya, Kohtaro,Tsuji, Etsushi,Katada, Naonobu

, p. 85 - 92 (2018)

Glycerol is a promising renewable feedstock for the manufacture of C3 derivatives. We investigated the one-pass oxidehydrarion of glycerol through the dehydration of glycerol into acrolein, followed by the oxidation of acrolein. A novel bifunctional catalyst for this reaction was prepared by loading the Keggin-type molybdovanadophosphoric acid H3+xPVxMo12-xO40 (x = 0–3) on ZSM-5 (MFI) zeolite (Si/Al = 45) exhibiting both dehydration and oxidation activity. H5PV2Mo10O40 and H6PV3Mo9O40 were stable and dispersed on ZSM-5 zeolite, and the acidic property of the ZSM-5 zeolite was retained. The oxidehydration of glycerol was catalyzed by H5PV2Mo10O40 loaded on the ZSM-5 zeolite with high selectivity of acrylic acid. In-situ IR analysis suggests that acrolein molecules adsorbed on H5PV2Mo10O40/ZSM-5 were converted into acrylic acid due to the inhibition of side-reactions such as polymerization and auto-condensation, which induced coke formation, compared with the other Mo and V-based oxides loaded on ZSM-5 zeolite.

Reaction coordinate analysis for β-diketone cleavage by the non-heme Fe2+-dependent dioxygenase Dke1

Straganz, Grit D.,Nidetzky, Bernd

, p. 12306 - 12314 (2005)

Acetylacetone dioxygenase from Acinetobacter johnsonii(Dke1) utilizes a non-heme Fe2+ cofactor to promote dioxygen-dependent conversion of 2,4-pentanedione (PD) into methylglyoxal and acetate. An oxidative carbon-carbon bond cleavage by Dke1 is triggered from a C-3 peroxidate intermediate that performs an intramolecular nucleophilic attack on the adjacent carbonyl group. But how does Dke1 bring about the initial reduction of dioxygen? To answer this question, we report here a reaction coordinate analysis for the part of the Dke1 catalytic cycle that involves O2 chemistry. A weak visible absorption band (ε ≈ 0.2 mM-1 cm-1) that is characteristic of an enzyme-bound Fe2+-β-keto-enolate complex served as spectroscopic probe of substrate binding and internal catalytic steps. Transient and steady-state kinetic studies reveal that O2-dependent conversion of the chromogenic binary complex is rate-limiting for the overall reaction. Linear free-energy relationship analysis, in which apparent turnover numbers (kcatapp) for enzymatic bond cleavage of a series of substituted β-dicarbonyl substrates were correlated with calculated energies for the highest occupied molecular orbitals of the corresponding β-keto-enolate structures, demonstrates unambiguously that k catapp is governed by the electron-donating ability of the substrate. The case of 2′-hydroxyacetophenone (2′HAP), a completely inactive β-dicarbonyl analogue that has the enol double bond delocalized into the aromatic ring, indicates that dioxygen reduction and C-O bond formation cannot be decoupled and therefore take place in one single kinetic step.

Crystalline Mo3VOx mixed-metal-oxide catalyst with trigonal symmetry

Sadakane, Masahiro,Watanabe, Nobufumi,Katou, Tomokazu,Nodasaka, Yoshinobu,Ueda, Wataru

, p. 1493 - 1496 (2007)

Outstanding catalytic activity for the selective oxidation of acrolein (see picture) is observed with a crystalline metal oxide, Mo3VO x (x ≤ 11.1). The catalyst is synthesized from a solution containing pentagonal units of {Mo(Mo5O27)} (blue), which further react with molybdenum and vanadium species (red) to form a 3D metal oxide. (Chemical Equation Presented).

Photocatalytic removal of benzene over Ti3C2T: XMXene and TiO2-MXene composite materials under solar and NIR irradiation

Calvino, José J.,Constantinescu, Gabriel,Frade, Jorge R.,Kovalevsky, Andrei V.,Labrincha, Jo?o A.,Lajaunie, Luc,Lopes, Daniela V.,Sergiienko, Sergii A.,Shaula, Aliaksandr L.,Shcherban, Nataliya D.,Shkepu, Viacheslav I.,Tobaldi, David M.

, p. 626 - 639 (2022/01/22)

MXenes, a family of two-dimensional (2D) transition metal carbides, nitrides and carbonitrides based on earth-abundant constituents, are prospective candidates for energy conversion applications, including photocatalysis. While the activity of individual MXenes towards various photocatalytic processes is still debatable, these materials were proved to be excellent co-catalysts, accelerating the charge separation and suppressing the exciton recombination. Titanium-containing MXenes are well compatible with the classical TiO2 photocatalyst. The TiO2 component can be directly grown on MXene sheets by in situ oxidation, representing a mainstream processing approach for such composites. In this study, an essentially different approach has been implemented: a series of TiO2-MXene composite materials with controlled composition and both reference end members were prepared, involving two different strategies for mixing sol-gel-derived TiO2 nanopowder with the Ti3C2Tx component, which was obtained by HF etching of self-propagating high-temperature synthesis products containing modified MAX phase Ti3C2Alz (z > 1) with nominal aluminium excess. The prospects of such composites for the degradation of organic pollutants under simulated solar light, using benzene as a model system, were demonstrated and analysed in combination with their structural, microstructural and optical properties. A notable photocatalytic activity of bare MXene under near infrared light was discovered, suggesting further prospects for light-to-energy harvesting spanning from UV-A to NIR and applications in biomedical imaging and sensors.

Photophysics of Perylene Diimide Dianions and Their Application in Photoredox Catalysis

Li, Han,Wenger, Oliver S.

supporting information, (2021/12/23)

The two-electron reduced forms of perylene diimides (PDIs) are luminescent closed-shell species whose photochemical properties seem underexplored. Our proof-of-concept study demonstrates that straightforward (single) excitation of PDI dianions with green

The influence of different carbonate ligands on the hydrolytic stability and reduction of platinum(

Chen, Shu,Deng, Zhiqin,Ng, Ka-Yan,Tse, Man-Kit,Yao, Houzong,Zhou, Qiyuan,Zhu, Guangyu

supporting information, p. 885 - 897 (2022/02/01)

Pt(iv) complexes bearing axial carbonate linkages have drawn much attention recently. A synthetic method behind this allows the hydroxyl group of bioactive ligands to be attached to the available hydroxyl group of Pt(iv) complexes, and the rapid release of free drugs is achieved after the reduction of carbonate-linked Pt(iv) complexes. Further understanding on the properties of Pt(iv) carbonates such as hydrolytic stability and reduction profiles, however, is hindered by limited research. Herein, six mono-carbonated Pt(iv) complexes in which the carbonate axial ligands possess various electron-withdrawing powers were synthesized, and the corresponding mono-carboxylated analogues were also prepared as references to highlight the different properties. The influence of the coordination environment towards the hydrolysis and reduction rate of Pt(iv) carbonates and carboxylates was explored. The mono-carbonated Pt(iv) complexes are both less stable and reduced faster than the corresponding mono-carboxylated ones. Moreover, the hydrolysis and reduction profiles are dependent not only on the electron-withdrawing ability of the carbonates but also on the nature of the opposite axial ligands. Besides, the exploration of the hydrolytic pathway for Pt(iv) carbonates suggests that the process proceeds by an attack of OH? on the carbonyl carbon, followed by elimination, which is different from that of Pt(iv) carboxylates. This study provides some information on the influence of axial carbonate ligands with different electron-withdrawing abilities on the properties of the Pt(iv) center, which may inspire new thoughts on the design of “multi-action” Pt(iv) prodrugs.

Photothermal strategy for the highly efficient conversion of glucose into lactic acid at low temperatures over a hybrid multifunctional multi-walled carbon nanotube/layered double hydroxide catalyst

Duo, Jia,Jin, Binbin,Jin, Fangming,Shi, Xiaoyu,Wang, Tianfu,Ye, Xin,Zhong, Heng

, p. 813 - 822 (2022/02/09)

The conversion of carbohydrates into lactic acid has attracted increasing attention owing to the broad applications of lactic acid. However, the current methods of thermochemical conversion commonly suffer from limited selectivity or the need for harsh conditions. Herein, a light-driven system of highly selective conversion of glucose into lactic acid at low temperatures was developed. By constructing a hybrid multifunctional multi-walled carbon nanotube/layered double hydroxide composite catalyst (CNT/LDHs), the highest lactic acid yield of 88.6% with 90.0% selectivity was achieved. The performance of CNT/LDHs for lactic acid production from glucose is attributed to the following factors: (i) CNTs generate a strong heating center under irradiation, providing heat for converting glucose into lactic acid; (ii) LDHs catalyze glucose isomerization, in which the photoinduced OVs (Lewis acid) in LDHs under irradiation further improve the catalytic activity; and (iii) in a heterogeneous-homogeneous synergistically catalytic system (LDHs-OH-), OH- ions are concentrated in LDHs, forming strong base sites to catalyze subsequent cascade reactions.

2-(4-Nitrophenyl)-1H-indolyl-3-methyl Chromophore: A Versatile Photocage that Responds to Visible-light One-photon and Near-infrared-light Two-photon Excitations

Abe, Manabu,Guo, Runzhao,Hamao, Kozue,Lin, Qianghua,Takagi, Ryukichi

supporting information, p. 153 - 156 (2022/02/14)

Due to cell damage caused by UV light, photoremovable protecting groups (PPGs) that are removed using visible or near-infrared light are attracting attention. A 2-(4-nitrophenyl)- 1H-indolyl-3-methyl chromophore (NPIM) was synthesized as a novel PPG. Various compounds were caged using this PPG and uncaged using visible or near-infrared light. Low cytotoxicity of NPIM indicates that it may be applied in physiological studies.

Process route upstream and downstream products

Process route

p-cresol
106-44-5

p-cresol

4-methyl-2-nitrophenol
119-33-5

4-methyl-2-nitrophenol

2,6-dinitro-p-cresol
609-93-8

2,6-dinitro-p-cresol

acetic acid
64-19-7,77671-22-8

acetic acid

propionic acid
802294-64-0,79-09-4

propionic acid

Conditions
Conditions Yield
beim Nitrieren;
6-methoxy-3-methyl-hept-2-en-4-one
103263-50-9

6-methoxy-3-methyl-hept-2-en-4-one

chloroform
67-66-3,8013-54-5

chloroform

3-methoxybutanoic acid
10024-70-1,16510-79-5

3-methoxybutanoic acid

acetic acid
64-19-7,77671-22-8

acetic acid

Conditions
Conditions Yield
bei der Ozonolyse;
heptadecan-2-one
2922-51-2

heptadecan-2-one

palmitic acid
1002-84-2

palmitic acid

acetic acid
64-19-7,77671-22-8

acetic acid

Conditions
Conditions Yield
With chromic acid;
methyltriacetoxysilane
4253-34-3

methyltriacetoxysilane

vinyl triacetoxy silane
4130-08-9

vinyl triacetoxy silane

octamethylsilsesquioxane
17865-85-9

octamethylsilsesquioxane

octavinylsilsesquioxane
69655-76-1

octavinylsilsesquioxane

acetic acid
64-19-7,77671-22-8

acetic acid

C<sub>9</sub>H<sub>24</sub>O<sub>12</sub>Si<sub>8</sub>

C9H24O12Si8

C<sub>10</sub>H<sub>24</sub>O<sub>12</sub>Si<sub>8</sub>

C10H24O12Si8

C<sub>15</sub>H<sub>24</sub>O<sub>12</sub>Si<sub>8</sub>

C15H24O12Si8

Conditions
Conditions Yield
With water; for 80h; Product distribution; several condition investigated;
3.5-Dinitro-aspirin, (O-Acetyl-3.5-dinitro-salicylsaeure)
19073-90-6

3.5-Dinitro-aspirin, (O-Acetyl-3.5-dinitro-salicylsaeure)

3,5-dinitrosalicylic acid
609-99-4

3,5-dinitrosalicylic acid

acetic acid
64-19-7,77671-22-8

acetic acid

Conditions
Conditions Yield
With water; In acetonitrile; at 25 ℃; Rate constant;
N-(4-Nitrophenyl)acetamide
104-04-1

N-(4-Nitrophenyl)acetamide

acetic acid
64-19-7,77671-22-8

acetic acid

4-nitro-aniline
100-01-6,104810-17-5

4-nitro-aniline

Conditions
Conditions Yield
With hydrogenchloride; In water; at 30 ℃; Rate constant; hydrolysis;
With cetyltrimethylammonim bromide; at 102.9 ℃; Mechanism; borate buffer pH 9.0; inhibition by var. salts added;
With Rhodococcus erythropolis TA37 acylamidase; water; tris hydrochloride; at 37 ℃; for 0.333333h; pH=7.5; Kinetics; Enzymatic reaction;
4-nitrophenol acetate
830-03-5

4-nitrophenol acetate

acetic acid
64-19-7,77671-22-8

acetic acid

Conditions
Conditions Yield
With (ZnII-(1,5,9-triazacyclododecane)(OH))3*(ClO4)3; water; at 25 ℃; Rate constant; pH 8.2, I = 0.10 (NaClO4);
With pH 8.2 phosphate buffer; water; β-DMCD bearing imidazolylethyl group; at 25 ℃; Rate constant; pH dependence of kcat is determined;
With poly<1-methyl-3-(2-hydroxyethyl)imidazolium bromide>; In ethanol; at 23.9 ℃; Rate constant; var. pH;
With hydrogenchloride; water; In water; at 25 ℃; Thermodynamic data; ΔGtrΘ, ΔHtrΘ, ΔStrΘ, ΔCpΘ of transfer;
With water; various imidazoles; at 25 ℃; Rate constant;
With MES-buffer; Alkyl-pyridine*Cu(2+); at 35 ℃; Rate constant; Mechanism; Equilibrium constant; pH 6.25;
cetyldimethyl-(2-hydroxyiminophenethy..; In ethanol; water; at 30 ℃; Rate constant; variuos catalysts, pH=8.0-8.8;
With disodium hydrogenphosphate; sodium dihydrogenphosphate; water; acetylcholinesterase; at 25 ℃; Rate constant; pH 7.50; isotope effect 0.992; further reagents;
With 1H-imidazole; water; In ethanol; at 25 ℃; Mechanism; Kinetics; phosphate buffer (pH=8.05);
With water; In 1,4-dioxane; at 25 ℃; Rate constant;
With 2-aminopyridine; water; at 30 ℃; Rate constant; Mechanism; other aminopyridines and aniline;
With phosphate buffer; H-His-Ser-Asp-Ala-OH; In 1,4-dioxane; at 25 ℃; Rate constant;
Z-Leu-His; at 25 ℃; Rate constant; Mechanism; pH=7.30, 0.02M phosphate buffer; further catalyst; effect of surfactants;
With buffer solution; pilocarpine hydrochloride; In water; acetonitrile; at 24.9 ℃; Rate constant; other catalysts, var. pH-values;
With N,N',N'',N'''-tetrakis-<10-decyl>-3,10,21,28-tetraoxo-2,11,20,29-tetra-aza<3.3.3.3>paracyclophane tetrachloride; In ethanol; water; at 30 ℃; Rate constant; other catalyst (three isomers containing two imidazolyl groups on adjacent and opposite alkyl chains); catalytic activity and substrate selectivity of both paracyclophanes compared; pH dependency of the substrate-binding ability of the cyclophanes;
With sodium glycocholic acid; water; at 37.4 ℃; Rate constant; var. concentration of other bile salts; var. pH; phosphate buffer;
With erythromycin A-hydrolyse prod.; water; In 1,4-dioxane; at 20 ℃; Rate constant; pH 11.972;
With water; cyclo-L-histydyl-L-histydyl; In 1,4-dioxane; at 20 ℃; Thermodynamic data; Kinetics; other p-nitrophenyl esters, var. catalyst and pH, ΔH, ΔS, ΔG;
With hydroxide; at 23 ℃; Mechanism; pH 9.0; 15N kinetic isotope effect; also reaction with phenol;
With Tris buffer; zinc(II) perchlorate; podant1 + Zn(ClO4)2; In water; acetonitrile; Rate constant; with other endodentate tripodand-Zn(2+)-complexes , variation of pH;
With borate buffer; hydroxide; In ethanol; water; at 25 ℃; Rate constant;
With water; In dimethyl sulfoxide; at 35 ℃; Kinetics; Thermodynamic data; pH=13.12; ΔH(excit.); -ΔS(excit.); different substrate concentrations, ratios of solvents and temperature;
apo-Mb semisynthetic enzyme; In water; at 25 ℃; Rate constant; Mechanism; buffer : 0.05 M Tris, pH 8;
With alkaline solution; In water; acetonitrile; at 24.9 - 25.1 ℃; Rate constant; carbonate buffer pH 10.70;
With borate buffer; water; C18H22F17N2O2(1+); In acetonitrile; at 30 ℃; Rate constant; var. further catalyst, catalyst concn.;
With sodium hydroxide; poly(trimethylvinylbenzylammonium chloride); at 25 ℃; Thermodynamic data; without PMVA and also with sodium poly(styrenesulfonate); ΔG(excit.), ΔH(excit.), ΔS(excit.);
With 1-methyl-1H-imidazole; water; In dichloromethane; also in the presence of NO and protoheme dimethyl ester;
With o-(N,N-dimethylaminomethyl)benzyl alcohol; water; at 25 ℃; Rate constant; var. ionic strength and pH, other tertiary amine as catalysts;
With Tris-HCl buffer; water; In acetonitrile; Rate constant; Kinetics; Thermodynamic data; IgG and IgM monoclonal antibodies as catalysts (antibody KD2-1 - KD2-260); var. temp., var. pH; ΔH(excit.), ΔG(excit.), ΔS(excit.);
With cetyltrimethylammonim bromide; 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine; In water; at 25 ℃; Kinetics; Tris buffer solution (pH=8.0); the effect of lecithin dispersed by surfactants on the rate hydrolysis;
α-chymotrypsin; In acetonitrile; at 10 - 57 ℃; Kinetics; Mechanism; ΔH(excit.), ΔS(excit.), ΔF(excit.), heat and pressure inactivation of α-chymotrypsin;
With phosphate buffer; N-(tert-butoxycarbonyl)-L-histidine methyl ester; In water; N,N-dimethyl-formamide; at 25 ℃; Rate constant; imidazole and other histidine-containing linear and cyclic peptides;
With 1-methyl-1H-imidazole; 2-(cyclohexylamino)ethanesulfonic acid; In acetonitrile; at 27 ℃; Rate constant; Mechanism; other p-nitrophenyl esters; other methyl-substituted imidazoles; solvent isotope effects;
With cetyltrimethylammonim bromide; (2S)-N-decanoyl-2-amino-3-(1H-imidazol-4-yl)propionic acid; at 25 ℃; Rate constant; other catalytic system; deacylation effect of bifunctional comicellar catalyst; pH 7.30;
With bis(2-ethylhexyl) sulfosuccinate; water; at 15 ℃; under 225018 Torr; Kinetics; examination of effects of pressure;
With water; at 24 ℃; Kinetics;
With 6-deoxy-6-(L-histydylamino)-β-cyclodextrin; In water; at 25 ℃; Rate constant; phosphate buffer pH 7.8; other cyclodextrin;
With Carbonate buffer; alpha cyclodextrin; In water; dimethyl sulfoxide; at 25 ℃; Rate constant; various solvents; also with β-cyclodextrin;
With dm-3 phosphate buffer; at 25 ℃; Rate constant; pH 11.60; also in the presence of cyclodextrins at var conc. and var. nucleophiles;
With water; In methanol; at 25 ℃; Thermodynamic data; Rate constant; the role of the ultrasonic irradiation; ΔH(excit.), ΔS(excit.) and ΔG(excit.) datas in the presence and absence of ultrasound; various cavitatingases; pH dependence; effect of ionic strength, the role of supercritical water;
With sodium nitrate; zinc; In acetonitrile; at 25 ℃; Rate constant; var. catalysts;
With 1H-imidazole; hydrogenchloride; potassium chloride; water; In acetonitrile; at 25.1 ℃; Rate constant; var. pH, conc.;
With dmap; phosphate buffer; cetyltrimethylammonim bromide; In cyclohexane; butan-1-ol; at 25 ℃; Rate constant; other dialkylaminopyridines; var. microemulsion's composition;
With phosphate buffer; Thr-Ala-Ser-His-Asp; In 1,4-dioxane; at 28 ℃; Rate constant; other reaction partner system;
With octa(dimethylaminopropyl)resorcin<4>arene; water; at 25 ℃; Rate constant; Mechanism; other carboxylic acid 4-nitrophenyl esters;
With hydrogenchloride; poly(Asp-Leu-His-Leu-Ser-Leu); 2-amino-2-hydroxymethyl-1,3-propanediol; In ethanol; at 25 ℃; Kinetics; Thermodynamic data; also with Asp-Leu-His-Leu-Ser-Leu hexamer; ΔE(excit.); ΔH(excit.); ΔF(excit.); ΔS(excit.); var. temp.;
With SULFAMIDE; carbonic anhydrase II; In water; acetonitrile; at 25 ℃; Rate constant; other reagents;
With pH 11.6 phosphate buffer; cetyltrimethylammonim bromide; sodium bromide; In acetonitrile; at 25 ℃; Rate constant;
With borate buffer; TMA-quaternized butyl methacrylate latex; water; at 30 ℃; Rate constant; also in the presense of other trimethylamine or tributylamine quaternized latexes;
With pH=5.1 buffer; polypeptide MN-42; In water; acetonitrile; at 16.9 ℃; Rate constant; other polypetides vith var. amino acids sequences;
With 1H-imidazole; water; In acetonitrile; at 5 - 35 ℃; Further Variations:; Temperatures; Solvents; Kinetics; Activation energy;
With 2-aminobenzimidazole grafted on polymer; potassium chloride; tris hydrochloride; In ethanol; at 30.85 - 49.85 ℃; pH=7.5; Further Variations:; Reagents; Temperatures; Kinetics; Thermodynamic data;
With acetate buffer; JNIIHR polypeptide; In acetonitrile; at 16.85 ℃; pH=5.1; Further Variations:; Reagents; Kinetics;
With cellulose acetate esterase from Neisseria sicca SB; tris hydrochloride; In water; at 30 ℃; pH=8.0; Enzyme kinetics;
With MES buffer; water; 1-Dodecyl-4-[1-(hydroxyimino)ethyl]pyridinium bromide; at 25 ℃; pH=7.2; Further Variations:; Reagents; Kinetics;
With dodecyltrimethylammonium bromide; fipronilβ-cyclodextrin; at 25 ℃; Further Variations:; Reagents; Kinetics; Alkaline hydrolysis;
With iron (III) chelate of 1,2-bis(2-hydroxybenzamido)ethane; water; In methanol; at 26.5 ℃; Further Variations:; Reagents; pH-values; Kinetics;
With PEG-8000; Tris buffer; trypsin; In acetonitrile; at 25 ℃; pH=7.7; Further Variations:; Reagents; Enzyme kinetics;
With human carbonic anhydrase I EC 4.2.1.1; Tris buffer; In water; acetonitrile; at 25 ℃; pH=7.8; Further Variations:; Reagents; Enzyme kinetics;
With sodium hydroxide; 2,2,4-trimethylpentane; sodium docusate; at 25 ℃; Further Variations:; Reagents; pH-values; Kinetics;
With AcAPLEPEYPGDNATPEQMHQYAHQLRRYINMLCONH2; In acetate buffer; at 16.85 ℃; pH=5.1; Further Variations:; pH-values; Reagents; Kinetics;
human serum albumin; In phosphate buffer; at 25 ℃; pH=7.4; Further Variations:; Catalysts; Temperatures; Activation energy;
With sodium phosphate buffer; Aspergillus niger ZD11 pyrethroid hydrolase; In acetonitrile; at 30 ℃; pH=6.8; Enzyme kinetics;
With sodium phosphate buffer; Klebsiella sp. ZD112 pyrethroid-hydrolyzing esterase; In acetonitrile; at 30 ℃; pH=7.0; Enzyme kinetics;
With Leu29Pro Pseudomonas fluorescens esterase; N,N-bis(2-hydroxyethyl)-2-aminoethanesulfonic acid buffer; at 25 ℃; pH=7.2; Further Variations:; Reagents; Enzyme kinetics;
With sodium acetate buffer; modified Argopore-NH2; In water; acetonitrile; pH=5.0; Further Variations:; Reagents; Kinetics; Product distribution;
With water; αC2DTC; In various solvent(s); at 25 ℃; for 0.2h; pH=9.0; Further Variations:; Catalysts; pH-values; reaction times; Kinetics;
With esterase antibody 522C2; In 1,4-dioxane; at 30 ℃; pH=7.5; Enzyme kinetics;
With water; dinuclear Zn; In acetonitrile; at 25 ℃; pH=9.0; Further Variations:; pH-values; Kinetics;
With 4-methyl-1H-imidazole; water; at 16.84 ℃; pH=5.1; Kinetics;
With potassium chloride; water; at 25 ℃; pH=12.7; Further Variations:; pH-values; Reagents; reagents ratios; Kinetics;
With aq. bis-Tris buffer; [N-(3-(MeO)2CH-benzoyl)-1-Bn-L-histidyl]hydrazine cyclodimer; at 25 ℃; pH=6.20; Further Variations:; pH-values; Reagents; Kinetics;
With Burkholderia xenovorans LB400 BphD; In phosphate buffer; at 25 ℃; pH=7.0; Further Variations:; Reagents; Enzyme kinetics;
With sodium hydroxide; cetyltrimethylammonim bromide; at 25 ℃; Further Variations:; Reagents; Kinetics;
With 1H-imidazole; water; In ethanol; Temperature; Kinetics; Activation energy; Mechanism;
With Zn(5,11,17,23-tetra-tert-butyl-25,27-bis[2-[N-(2-hydroxybenzylidene)amino]ethoxy]-26,28-dihydroxycalix[4]arene); water; In acetonitrile; at 25 ℃; pH=8.27; pH-value; Kinetics;
With 6-aminohexanoate cyclic dimer hydrolase Arthrobacter sp.; at 30 ℃; pH=7; aq. phosphate buffer; Enzymatic reaction;
With Acinetobacter johnsonii dioxygenase Dke1; at 25 ℃; pH=7.5; Reagent/catalyst; Time; Kinetics; aq. buffer; Enzymatic reaction;
With human intestinal carboxylesterase; pH=7.4; Reagent/catalyst; Kinetics; aq. buffer; Enzymatic reaction;
With water; Fe2O3-Cys-Lys nanocomplex; at 37 ℃; for 48h; pH=7; Conversion of starting material;
With EstEH112 esterase; water; at 25 ℃; pH=8; GTA buffer; Enzymatic reaction;
With potassium chloride; water; 1,6-bis(N-hexadecyl-N,N-dimethylammonium)hexane dibromide; sodium hydroxide; at 25 ℃; Reagent/catalyst; Kinetics;
With sodium nitrate; C18H44Cu2N6O2(2+)*2ClO4(1-); water; In acetonitrile; for 25h; pH=8.8; Reagent/catalyst; Time; pH-value; Kinetics; Catalytic behavior;
With Pseudomonas fluorescens esterase; In aq. buffer; at 23 ℃; pH=7.2; Reagent/catalyst; Kinetics; Enzymatic reaction;
With Candida antarctica lipase B; In aq. phosphate buffer; at 20 ℃; pH=7; Reagent/catalyst; Kinetics; Enzymatic reaction;
With carboxylesterase EstSt7 from Sulfolobus tokodaii strain 7; water; In ethanol; at 80 ℃; pH=9; Kinetics; Enzymatic reaction;
With lipase from Candida rugosa; In aq. phosphate buffer; pH=7; pH-value; Enzymatic reaction;
With recombinant esterase from Rhizomucor miehei; In isopropyl alcohol; at 50 ℃; for 0.166667h; pH=7.5; Catalytic behavior; Kinetics; Enzymatic reaction;
With lipase PS from Burkholderia cepacia, immobilized in calcium carbonate microcapsule; In acetone; at 25 ℃; pH=7.0; Catalytic behavior; Enzymatic reaction;
With SLMKDTDSEE EIREAFRVFD KDGNGYISAA ELRHVMTNLG EKLTDEEVDE MIREADIDGD GQVNYEEFVQ HMTAK*; water; sodium chloride; calcium chloride; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid; In acetonitrile; pH=7.5; Reagent/catalyst; Kinetics; Enzymatic reaction;
With Burkholderia species lipoprotein lipase; C35H61NO17; water; In aq. phosphate buffer; at 25 ℃; pH=7.0; Kinetics; Catalytic behavior; Enzymatic reaction;
With Dactylosporangium aurantiacum subsp. Hamdenensis NRRL 18085 esterase WDEst17; water; In acetonitrile; at 40 ℃; pH=8.5; pH-value; Temperature; Solvent; Reagent/catalyst; Catalytic behavior; Kinetics; Enzymatic reaction;
With human carbonic anhydrase; In water; pH=7.4; Enzymatic reaction;
With C20H18N6; water; In aq. phosphate buffer; at 25 ℃; pH=7.6; Reagent/catalyst; Solvent; Kinetics; Irradiation; Darkness;
With Dactylosporangium aurantiacum esterase WDEst9; In aq. phosphate buffer; ethanol; acetonitrile; at 35 ℃; for 0.0833333h; pH=7.5; Catalytic behavior; Enzymatic reaction;
With water; In toluene; at 25 ℃; Kinetics; Enzymatic reaction;
In aq. buffer; at 25 ℃; pH=9;
With water; Rhizopus oryzae ZAC3 lipase; In aq. phosphate buffer; isopropyl alcohol; pH=8; Enzymatic reaction;
chlorobenzene
108-90-7

chlorobenzene

formic acid
64-18-6

formic acid

2-monochlorophenol
95-57-8

2-monochlorophenol

3-Nitrochlorobenzene
121-73-3

3-Nitrochlorobenzene

acetic acid
64-19-7,77671-22-8

acetic acid

4-chlorobenzonitrile
100-00-5

4-chlorobenzonitrile

2-Chloronitrobenzene
88-73-3

2-Chloronitrobenzene

Conditions
Conditions Yield
With ozone; hydrazine; at 22.9 ℃; for 0.75h; Product distribution; different reagent concentrations, times;
p-Nitrophenyl laurate
1956-11-2

p-Nitrophenyl laurate

acetic acid
64-19-7,77671-22-8

acetic acid

Conditions
Conditions Yield
With cetyltrimethylammonim bromide; N-decanoyl-L-histidine; at 25 ℃; Rate constant; other catalytic system; deacylation effect of bifunctional comicellar catalyst; pH 7.30;
p-nitrophenyl hexanoate
956-75-2

p-nitrophenyl hexanoate

acetic acid
64-19-7,77671-22-8

acetic acid

Conditions
Conditions Yield
With cetyltrimethylammonim bromide; N-decanoyl-L-histidine; at 25 ℃; Rate constant; other catalytic system; deacylation effect of bifunctional comicellar catalyst; pH 7.30;

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