87-42-3Relevant articles and documents
Synthesis of (purin-6-yl)acetates and 6-(2-hydroxyethyl)purines via cross-couplings of 6-chloropurines with the Reformatsky reagent
Hasník, Zbyněk,?ilhár, Peter,Hocek, Michal
, p. 5589 - 5592 (2007)
A novel approach to the synthesis of 6-(2-hydroxyethyl)purines was developed based on Pd-catalyzed cross-coupling reactions of 6-chloropurines with the Reformatsky reagent followed by reduction by NaBH4 and treatment with MnO2. This methodology was successfully applied to the syntheses of 6-(ethoxycarbonylmethyl)- and 6-(hydroxyethyl)purine bases and nucleosides.
Pyrimidinethione-containing purine compound and application thereof
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Paragraph 0018-0021, (2020/01/25)
The invention discloses a pyrimidinethione-containing purine compound having a structure represented by a formula I shown in the specification and an application of the compound as a plant growth regulator. The compound represented by the formula I has excellent cell division activity and plant growth regulating activity of promoting rooting, increasing the yield and improving the quality, and canbe widely used for rooting, seedling strengthening, yield increasing and quality improvement of crops such as grain, cotton, fruits and vegetables or plants through the manners of treating seeds, being sprayed to roots and stem leaves, at the same time, the compound represented by the formula I has a bactericidal effect, and the characteristics of safe use, low costs, and significant effects.
Hetero-aromatic compound and its use in medicine
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Paragraph 1374; 1377-1379, (2019/07/04)
The invention provides a hetero-aromatic compound or a stereisomer, geometric isomer, tautomer, despinner, nitrogen oxide, hydrate, solvate, metabolite, metabolism precursor and pharmaceutically acceptable salt or prodrug thereof, which is used for treating proliferative diseases. The invention also discloses a pharmaceutical composition containing the compound and an application of the compound or pharmaceutical composition thereof in preparation of a medicine for treating proliferative diseases.