Quelet Reaction

R. Quelet, Compt. Rend. 195, 155 (1932).

Passage of dry hydrochloric acid through a solution in ligroin of a phenolic ether and an aliphatic aldehyde in the presence or absence of a dehydration catalyst to yield α-chloroalkyl derivatives by substitution in the para position to the ether group or in the ortho position in para-substituted phenolic ethers:



R. Quelet, ibid. 196, 1411 (1933); 198, 102 (1934); 199, 150 (1934); 202, 956 (1936); Bull. Soc. Chim. France 7, 196 (1940); U. Neda, R. Oda, J. Soc. Chem. Ind. Japan 47, 565 (1944). Cf. Blanc (Chloromethylation) Reaction.