- Synthesis of Etilefrine pivalate hydrochloride
-
(CAS NO.: ), with its systematic name of Benzyl alcohol, alpha-((ethylamino)methyl)-m-hydroxy-, 2,2-dimethylpropionate, hydrochloride, could be produced through many synthetic methods.

(I) is acylated with pivaloylchloride (II) to produce 3-pivaloyloxyacetophenone (III). The latter is brominated with bromine to 3-pivaloyloxy-2-bromoacetophenone (IV), which in turn reacts with N-ethylbenzylamine (V) to form 3-pivaloyloxy-2-(benzylethylamino)acetophenone (VI). This compound is debenzylated and reduced with H2 in the presence of Pd/C in isopropanol containing hydrochloric acid to yield etilefrine pivalate hydrochloride.
Prev:No record
Next:No record - 【Back】【Close 】【Print】【Add to favorite 】
- Related information
- Production Method of Pentacaine hydrochloride
- One Synthetic Approach of Mirfentanil hydrochloride
- Production Method of Sarpogrelate hydrochloride
- Production Route of Terflavoxate hydrochloride
- One Synthetic Approach of Lazabemide hydrochloride
- Synthesis of Levobunolol hydrochloride
- Synthetic Method of Mexidol hydrochloride
- Synthesis of Tiospirone hydrochloride
- Synthetic Methods of Guanfacine hydrochloride
- Production of Labetalol hydrochloride
-
Health and Chemical more >
-
Hot Products
- 842124-02-1 3-(1,3-Dioxolan-2-yl)-1-(3-fluorophenyl)propan-1-one
- 19398-61-9 2,5-DICHLOROTOLUENE
- 10545-99-0 Sulfur dichloride
- 976-70-5 3-oxopregn-4-ene-21,17alpha-carbolactone
- 16679-58-6 Desmopressin
- 68130-33-6 Hexanedioic acid, polymer with 2,2-bis(hydroxymethyl)-1,3-propanediol, (9Z)-9-octadecenoate
- 922-65-6 1,4-Pentadien-3-ol
- 13569-75-0 CHROMIUM (IC) IODIDE
- 431-07-2 1-chloro-1,2,2-trifluoro-ethane
- 7560-83-0 N,N-Dicyclohexylmethylamine
- 149968-11-6 METHYL 2-(3-{(E)-3-[2-(7-CHLORO-2-QUINOLYL)VINYL]PHENYL}-3-OXOPROPYL)BENZOATE
- 111998-18-6 Hexanal, 6-cyclopentylidene-


