Cefteram pivaloyloxy (CAS NO.: ), with other name of , could be produced through many synthetic methods.

Following is one of the synthesis routes: 7-Aminocephalosporanic acid (I) is condensed with 5-methyltetrazole (II) in the presence of BF₃ ethyl ether in sulfolane to produce 7-amino-3-(5-methyl-1,2,3,4-tetrazol-2-ylmethyl)-3-cephem-4-carboxylic acid (III), which is esterified with pivaloyloxymethyl iodide (IV) by means of triethylamine in DMF yielding the corresponding ester (V). Finally, this compound it condensed with 2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetic acid (VI) by means of POCl₃ and dimethylacetamide in CH₂Cl₂.