Synthesis and evaluation of bibenzyl glycosides as potent tyrosinase inhibitors

DOI: 10.1016/j.ejmech.2011.01.065

Source and publish data:

European Journal of Medicinal Chemistry p. 1374 - 1381 (2011)

Update date:2022-08-04

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Authors:

Tajima, Reiko

Oozeki, Hiromi

Muraoka, Seiichi

Tanaka, Saori

Motegi, Yukari

Nihei, Hiroyuki

Yamada, Yoichi

Masuoka, Noriyoshi

Nihei, Ken-Ichi

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Article abstract of DOI:10.1016/j.ejmech.2011.01.065

Bibenzyl glycosides 1-6 were synthesized from 2,4-dihydoxybenzaldehyde and xylose, glucose, cellobiose or maltose. The key steps in the synthesis were the Wittig reaction and trichloroacetimidate glycosylation. Tests for tyrosinase inhibitory activity sho

Full text of DOI:10.1016/j.ejmech.2011.01.065

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Product name:2',4'-dibenzyloxy-2,4-di(methoxymethoxy)bibenzyl

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