Tetrahedron Letters p. 1623 - 1626 (2008)
Update date:2022-08-03
Topics:
Takada, Keisuke
Takemura, Nobuko
Cho, Kaori
Sohtome, Yoshihiro
Nagasawa, Kazuo
Asymmetric nitroaldol reaction of α-ketoesters was explored using a guanidine-thiourea bifunctional organocatalyst at temperatures below the freezing point of water. The new reaction protocol can be applied to the nitroaldol reaction of nitroalkanes and α
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