Organic and Biomolecular Chemistry p. 1108 - 1113 (2008)
Update date:2022-08-04
Topics:
Duguet, Nicolas
Campbell, Craig D.
Slawin, Alexandra M. Z.
Smith, Andrew D.
N-Heterocyclic carbenes promote the formal [2+2] cycloaddition of ketenes with N-tosyl imines to give the corresponding β-lactams in good to excellent isolated yields; chiral NHCs give β-lactams in high e.e. after crystallisation.
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