
European Journal of Medicinal Chemistry p. 207 - 217 (1992)
Update date:2022-08-04
Topics:
Barraclough
Black
Cambridge
Capon
Cox
Firmin
Gerskowitch
Giles
Glen
Hill
Hull
Iyer
Kettle
King
Nobbs
Randall
Skone
Smith
Vine
et al.
A series of 2-arylimidazo[1,2-a]pyrimidines has been prepared and evaluated for inotropic activity. Three of these heterocycles, ether 19, sulphide 21 and mesylate 24 displayed more potent inotropic effects in vitro than isomazole. The in vivo inotropic p
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