New synthesis of a taxol A-ring system

DOI: 10.1016/S0040-4020(01)86347-X

Source and publish data:

Tetrahedron p. 2701 - 2710 (1993)

Update date:2022-08-02

Topics:

Authors:

Polla Polla

Frejd Frejd

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Article abstract of DOI:10.1016/S0040-4020(01)86347-X

The optically active taxol A-ring unit 3 was synthesized in 11 steps from 2-isopropyl-2-propenol. The stereogenic centers were introduced via the asymmetric glyoxylate-ene reaction and the Sharpless asymmetric epoxidation reaction.

Full text of DOI:10.1016/S0040-4020(01)86347-X

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