Stereoselective synthesis of optically active substituted piperidines and pyrrolidines from amino acid derivatives by titanium(II)mediated intramolecular cyclization reaction

Article abstract of DOI:10.1016/S0040-4039(97)10261-1

A versatile and high-yielding synthesis of optically active substituted piperidines and pyrrolidines from amino acid derivatives employing titanium(II)mediated intramolecular cyclization of bis-unsaturated carbonates was developed.