A stereocontrolled synthesis of monofluoro ketomethylene dipeptide isosteres

DOI: 10.1016/S0040-4039(98)00783-7

Source and publish data:

Tetrahedron Letters p. 4195 - 4198 (1998)

Update date:2022-08-04

Topics:

Authors:

Huffman, Robert V.

Junhua, Tao

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(98)00783-7

A simple, stereocontrolled synthesis of monofluoro ketomethylene dipeptide isosteres has been developed. The method is short (6 steps) and diastereoselective (85-95% de) and enantioselective (>95% ee).

Full text of DOI:10.1016/S0040-4039(98)00783-7

Products guided by the article

Product name:(Z)-(2R,5S)-6-Phenyl-2-propyl-4-trimethylsilanyloxy-5-(trityl-amino)-hex-3-enoic acid methyl ester

Cas No:1027936-13-5

R&D Labs maybe for 1027936-13-5

Beijing Stable Chemcial Co.ltd

Contact:86-10-63785052

Address:A1301 Technological Edifice. No.4 FuFeng Road,FengTai District, Beijing. China
Wuhan Chemwish Technology Co., Ltd

website:http://www.chemwish.com/

Contact:+86-27-67849912

Address:Room 1311, Unit 2, Block1, Innovation Road East Lake High-tech Development Zone Wuhan, Hubei，P.R. China
Acorn PharmaTech Co., Ltd

Contact:86-25-58619180

Address:Nanjing High-Tech Zone 10 Xinghuo Road Pukou District Nanjing, Jiangsu 210061 The People's Republic of China
Taiwan Surfactant Corp.

Contact:886 2 2541 0022

Address:8 Fl., No. 11, Sec. 1, Chung Shan North Rd., Taipei, Taiwan R.O.C.
feixia327@163.com

Contact:--

Address:80G, No.1 Building, Guodu Development Mansion, No. 182 Zhaohui Road, Hangzhou City, Zhejiang Province,China.

Relevant to this article

Synthesis of novel 4,6-disubstituted quinazoline derivatives, their anti-inflammatory and anti-cancer activity (cytotoxic) against U937 leukemia cell lines

Doi:10.1016/j.ejmech.2007.06.010
(2008)
Syntheses and biological activities of new N₁-aryl substituted quinolone antibacterials

Doi:10.1002/ardp.19963290403
(1996)
The mechanism of 1,4 alkyl group migration in hypervalent halonium ylides: The stereochemical course

Doi:10.1021/ja802735f
(2008)
Versatile scorpionates and new developments in the denticity changes of NNCp hybrid scorpionate/cyclopentadienyl ligands in Sc and Y compounds: From κ¹-Nη⁵-Cp to κ²- NNη⁵-Cp

Doi:10.1021/ic800267v
(2008)
Crystallographic characterization of helical secondary structures in α/β-peptides with 1:1 residue alternation

Doi:10.1021/ja800355p
(2008)
Synthesis and Biological Activity of Substance P C-Terminal Hexapeptide Analogues: Structure-Activity Studies

Doi:10.1021/jm00157a028
(1986)

Article Doi