A stereocontrolled synthesis of monofluoro ketomethylene dipeptide isosteres

DOI: 10.1016/S0040-4039(98)00783-7

Source and publish data:

Tetrahedron Letters p. 4195 - 4198 (1998)

Update date:2022-08-04

Topics:

Authors:

Huffman, Robert V.

Junhua, Tao

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Article abstract of DOI:10.1016/S0040-4039(98)00783-7

A simple, stereocontrolled synthesis of monofluoro ketomethylene dipeptide isosteres has been developed. The method is short (6 steps) and diastereoselective (85-95% de) and enantioselective (>95% ee).

Full text of DOI:10.1016/S0040-4039(98)00783-7

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