
Tetrahedron Letters p. 4195 - 4198 (1998)
Update date:2022-08-04
Topics:
Huffman, Robert V.
Junhua, Tao
A simple, stereocontrolled synthesis of monofluoro ketomethylene dipeptide isosteres has been developed. The method is short (6 steps) and diastereoselective (85-95% de) and enantioselective (>95% ee).
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