Chiral Recognition in Aqueous Solution. Search for Water-Soluble Chiral Hosts with Apolar Binding Sites

Article abstract of DOI:10.1021/jo00367a005

Macrocycles 1a/1b with terasubstituted biphenyl units as chiral barriers are designed as potential hosts for the optical resolution of racemic aromatic guests with anionic residues.Synthetic attempts to prepare from a planar arene, pyrene, a chiral biphen