Modification of Guanine Bases: Reaction of N2-Acylated Guanine Nucleosides with Dichloro-(N,N-diisopropylamino)phosphine

DOI: 10.1021/jo00368a037

Source and publish data:

Journal of Organic Chemistry p. 3559 - 3560 (1986)

Update date:2022-08-03

Topics:

Authors:

Damha, Masad J.

Ogilvie, Kelvin K.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00368a037

N²-acylated guanine nucleosides (acyl = benzoyl, isobutyryl, acetyl) reacted rapidly with dichloro-(N,N-diisopropylamino)phosphine in the presence of diisopropylethylamine to give novel phosphitylated tricyclic guanine nucleoside derivatives in

Full text of DOI:10.1021/jo00368a037

Products guided by the article

Product name:3-[(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-8-diisopropylamino-6-phenyl-3H-7-oxa-1,3,4,5,8a-pentaaza-8-phospha-cyclopenta[b]naphthalen-9-one

Cas No:103457-18-7

R&D Labs maybe for 103457-18-7

jiangsu hualin chemical co.,ltd.

Contact:86-25-87787402

Address:jaingsu,china
Hubei Xiangxi Chemical Industry Co.,Ltd

Contact:+86-710-3454830

Address:No.7, Daqing East Road, Xiangfan City, Hubei Province, China
Jining Shengrun Chemical Industry Co., Ltd.

Contact:+86-537-7121666 ,

Address:West Ring Road,Wenshang County Shandong Province
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

website:http://www.shydtec.com

Contact:86-21-57721279

Address:Science and Technology Park, Songjiang District, Shanghai, China
Jinan Kaypharm Chemical Co.,Ltd

Contact:86-0531-86986780

Address:Room101,No189-2,Huayuan Road,Jinan City,Shandong Province

Relevant to this article

Novel γ-aminobutyric acid ρ₁ receptor antagonists; synthesis, pharmacological activity and structure-activity relationships

Doi:10.1021/jm7015842
(2008)
Successive copper(I)-catalyzed cross-couplings in one pot: A novel and efficient starting point for synthesis of carbapenems

Doi:10.1021/ol800845r
(2008)
SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF DERIVATIVES OF 2,4-DICHLORO-5-SULFAMOYLBENZOIC ACID

Doi:10.1007/BF00767172
(1985)
Doi:10.1021/jo01269a090
(1968)
Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer

Doi:10.1016/j.bmcl.2011.01.071
(2011)
ASYMMETRIC SYNTHESIS VII¹: ENANTIOSPECIFIC PREPARATION OF β-AMINOALCOHOLS FROM THE N-CYANOMETHYL-4-PHENYL-1,3-OXAZOLIDINE SYNTHON

Doi:10.1016/S0040-4039(01)84595-0
(1985)

Article Doi