Tetrahedron p. 501 - 514 (1986)
Update date:2022-08-03
Topics:
Matsuzaki, Jun-ichi
Hotoda, Hitoshi
Sekine, Mitsuo
Hata, Tsujiaki
Higuchi, Shigesada
et al.
Eight kinds of self-complementary tetradeoxyribonucleoside triphosphates were prepared by a simplified method which enabled us to omit purification of synthetic intermediates and provided the tetramers very rapidly and conveniently.The tetramers were characterized by enzyme assay and their conformations were studied by the use of UV and CD spectroscopic methods under various conditions.The detailed analysis of the CD spectra suggested that conformation of the tetramer duplexes was dependent on the sequence.
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