Steroids p. 59 - 64 (1990)
Update date:2022-08-03
Topics:
Avery, Mitchell A.
Tanabe, Masato
Crowe, David F.
Detre, George
Peters, Richard H.
Chong, Wesley K. M.
The title compound, 17aβ-hydroxy-7α-methyl-D-homoestra-4, 16-dien-3-one (3), was synthesized in five steps (17percent overall yield) from 7α-methylestrone methyl ether (5) and was found to possess oral androgenic activity, in excess of other known androgens, without using 17α-alkyl substitution. (Steroids 55:59-64, 1990)
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