A novel, nonsteroidal inhibitor of androgen binding to the rat androgen binding protein: Diethyl [[[3-(2,6-dimethyl-4-pyridinyl)-4-fluorophenyl]amino]methylene]propane dioate

Article abstract of DOI:10.1021/jm00163a021

In vitro binding studies demonstrate the binding specificity of a series of 4-aryl-2,6-dimethylpyridines for the rat epididymal androgen binding protein (rABP). The compounds bound competitively to rABP but have very weak or no demonstrable affinity for r