Lanthanide- and DMSO-Induced Ring Opening of 2-Iminooxetanes: Synthesis of β-Lactams and β-Keto Amides

Article abstract of DOI:10.1021/jo00109a038

2-Iminooxetanes (1), generated by lanthanide-catalyzed heterocycloaddition of aldehydes to ketene imines, are versatile synthons for β-lactams (2) and for β-keto amides (3).Conversion of 1 into 2 and 3 can be accomplished by either lanthanide-induced or o