Substituent Effect on the Chemical Behaviour of some Carbonyl Compounds and Ketals with 1-Ethoxy-3-Trimethylsilyl-prop-1-yne

Article abstract of DOI:10.1016/0040-4039(94)85065-8

In this work, principal component analysis (PCA) was carried out on the basis of property descriptors for a set of carbonyl compounds and ketals.A principal component projection of the points representing the compounds showed that the chemical behaviour of the compounds with 1-ethoxy-3-trimethylsilylprop-1-yne is related to their chemical composition.The obtained structure-chemical behaviour information was used to design a space transition state of the studied reactions.