Hypervalent Organoiodine-Promoted Oxidative Ring Expansions of Tributylstannyl Lactols. New and General Synthesis of Unsaturated Medium-Ring Lactones

Article abstract of DOI:10.1246/cl.1987.133

A new ring expansion route to olefinic lactones was developed.Oxidative 1,4-fragmentation of tributylstannyl lactols utilizing (diacetoxyiodo)benzene under mild conditions gave unsaturated medium-ring lactones stereospecifically in good yields.The relativ