Facile synthesis of high affinity styrylpyridine systems as inherently fluorescent ligands for the estrogen receptor

Article abstract of DOI:10.1016/S0960-894X(98)00652-0

A series of styrylpyridine derivatives containing two phenols was prepared via an efficient two-step synthesis. These compounds were designed to maximize the estrogen receptor binding affinity of a known series of inherently fluorescent styrylpyridines. W