SELECTIVE REDUCTION OF THE N-N BOND OF FUSED TETRAHYDROPYRIDAZINES: A ROUTE TO FUNCTIONALISED LACTAMS

DOI: 10.1016/S0040-4039(01)81045-5

Source and publish data:

Tetrahedron Letters p. 1573 - 1576 (1987)

Update date:2022-08-03

Topics:

Authors:

Gilchrist, Thomas L.

Hughes, Deborah

Wasson, Robert

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(01)81045-5

The C=N bond of 4,4a,5,6-tetrahydropyrrolo<1,2-b>pyridazin-7(3H)-ones (3) is reduced with high stereoselectivity by hydrogen over Adams' catalysts; the products (6) are N-acetylated and the N-N bond can then be cleaved by sodium in liquid ammonia to give

Full text of DOI:10.1016/S0040-4039(01)81045-5

Products guided by the article

Product name:N-[(1R,2R)-2-((R)-5-Oxo-pyrrolidin-2-ylmethyl)-cyclohexyl]-acetamide

Cas No:111097-36-0

R&D Labs maybe for 111097-36-0

Nanjing Chemical Material Corp.(NCMC)

website:http://www.njchemm.com

Contact:0086-25-83172879

Address:B12 Technology and Innovation Building, Nanjing Tech University, No.5 New Model Road
Shanghai Egoal Chemical Co.,Ltd

Contact:+86-21-50333091

Address:Yangming Garden Square 3,YangGao North Road 1188, Pudong New District, Shanghai
Jining Shengrun Chemical Industry Co., Ltd.

Contact:+86-537-7121666 ,

Address:West Ring Road,Wenshang County Shandong Province
Fusilin chemical science & technology co., ltd.

Contact:532-80698166/86057573, +86-400-669-7885

Address:School of Material Science & Engineering, Shandong Uinversity of Science & Technology, Huangdao Zone, Qindao, Shandong
Xiamen XM-Innovation Chemical Co., Ltd

Contact:+86-592-3216205

Address:Unit Q, 11/F, No.1 Office Building, Wuyuan Bay Business Center, Huli District, Xiamen City, Fujian Province, P.R.C

Relevant to this article

Intramolecular Azide-Olefin Cycloadditions. A Novel Synthesis of 2,5-Dihydrooxazoles

Doi:10.1021/jo00236a007
(1988)
Syntheses of 6-fluoro-7-piperazin-l-yl-9-cyclopropyl- 2,3,4,9-tetrahydroisothiazolo[5,4-b]quinoline-3,4-dione and 6-fluoro-7-piperazin-l-yl-9-p-fluorophenyl-2,3,4,9- tetrahydroisothiazolo[5,4-b]quinoline-3,4-dione[1]

Doi:10.1002/jhet.5570270404
(1990)
Synthesis and crystal structure of a novel molecular clip from diphenylglycoluril and phthalhydrazide

Doi:10.3184/030823410X12674504959007
(2010)
2-(4-CYANOPHENYL)-5-ARYLOXAZOLES

Doi:10.1007/BF00478140
(1986)
Enantioselective C-H Olefination of α-Hydroxy and α-Amino Phenylacetic Acids by Kinetic Resolution

Doi:10.1002/anie.201510808
(2016)
Doi:10.1016/0040-4020(68)88187-6
(1968)

Article Doi