Synthesis of piperazine derivatives and evaluation of their antihistamine and antibradykinin effects

DOI: 10.1016/S0960-894X(99)00471-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2727 - 2730 (1999)

Update date:2022-08-04

Topics:

Authors:

Choo, Hea-Young Park

Chung, Bum-Jun

Chung, Sung-Hyun

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Article abstract of DOI:10.1016/S0960-894X(99)00471-0

Piperazine derivatives were prepared as histamine antagonists. Some of the synthesized compounds showed dual antagonistic activity against bradykinin as well as histamine.

Full text of DOI:10.1016/S0960-894X(99)00471-0

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