ALKYLATION OF SHIFF BASE ANIONS WITH ω-HALOGENO ESTERS: A LACTAM SYNTHESIS.

DOI: 10.1016/S0040-4039(00)84971-0

Source and publish data:

Tetrahedron Letters p. 4435 - 4436 (1986)

Update date:2022-08-04

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Authors:

Mkhairi, A

Hamelin, J.

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Article abstract of DOI:10.1016/S0040-4039(00)84971-0

Imine anions of α-aminoesters, obtained from NaH/DMSO are alkylated with ω-halogenoesters.Thermolysis of the alkylated compounds lead to functionnalized lactams.

Full text of DOI:10.1016/S0040-4039(00)84971-0

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