Journal of Medicinal Chemistry p. 6962 - 6965 (2009)
Update date:2022-09-26
Topics:
Pelletier, Jeffrey C.
Lundquist IV, Joseph T.
Gilbert, Adam M.
Alon, Nipa
Bex, Frederick J.
Bhat, Bheem M.
Bursavich, Mattew G.
Coleburn, Valerie E.
Felix, Luciana A.
Green, Daniel M.
Green, Paula
Hauze, Diane B.
Kharode, Yogendra P.
Lam, Ho-Sun
Lockhead, Susan R.
Magolda, Ronald L.
Matteo, Jeanne J.
Mehlmann, John F.
Milligan, Colleen
Murrills, Richard J.
Pirrello, Jennifer
Selim, Sally
Sharp, Michael C.
Unwalla, Ray J.
Vera, Matthew D.
Wrobel, Jay E.
Yaworsky, Paul
Bodine, Peter V. N.
A high-throughput screening campaign to discover small molecule leads for the treatment of bone disorders concluded with the discovery of a compound with a 2-aminopyrimidine template that targeted the Wnt β-catenin cellular messaging system. Hit-tolead in
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