The synthetic potential of C-halophosphaalkenes

Article abstract of DOI:10.1080/10426509608545221

Methodologies for the functionalization of phosphaalkenes Mes*P=CHal₂ were developed. Lithiation with n-butyllithium yielded carbenoids Mes*P=CLiHal which were reacted with various electrophiles such as acid chlorides, carbonyl compounds, and metal halides. The dihalophosphaalkenes were also converted to monohalophosphaalkenes; the latter proved to be suitable for Stille-type cross coupling reaction with Grignard reagents. New phosphaalkenes of the type (E)-Mes*P=C(H)Ar with a variety of functionalities were obtained in high yield and isomeric purity.

Full text of DOI:10.1080/10426509608545221

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Phosphorus, Sulfur, and Silicon and
the Related Elements
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The Synthetic Potential of C-
Halophosphaalkenes
Marcel Van Der Sluis , Jan B. M. Wit & Friedrich
Bickelhaupt
a Scheikundig Laboratorium, Vrije Universiteit , De
Boelelaan 1083, NL-1081 HV Amsterdam, The Netherlands
b Scheikundig Laboratorium, Vrije Universiteit , De
Boelelaan 1083, NL-1081 HV Amsterdam, The Netherlands
c Scheikundig Laboratorium, Vrije Universiteit , De
Boelelaan 1083, NL-1081 HV Amsterdam, The Netherlands
Published online: 06 Aug 2008.
To cite this article: Marcel Van Der Sluis , Jan B. M. Wit & Friedrich Bickelhaupt (1996)
The Synthetic Potential of C-Halophosphaalkenes, Phosphorus, Sulfur, and Silicon and the
Related Elements, 109:1-4, 585-588, DOI: 10.1080/10426509608545221
To link to this article: http://dx.doi.org/10.1080/10426509608545221
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