Pumiliotoxin Alkaloids: Relationship of Cardiotonic Activity to Sodium Channel Activity and Phosphatidylinositol Turnover

DOI: 10.1021/jm00397a036

Source and publish data:

Journal of Medicinal Chemistry p. 477 - 480 (1988)

Update date:2022-07-30

Topics:

Authors:

Daly, J.W.

McNeal, E.

Gusovsky, F.

Ito, F. Ito, F.

Overman, L.E.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00397a036

The cardiotonic activity of pumiliotoxin B (PTX-B, 6-(6',7'-dihydroxy-2',5'-dimethyl-(E)-4'-octenylidene)-8-hydroxy-8-methyl-1-azabicyclo<4.3.0>nonane) as assessed in guinea pig atrial preparations is markedly dependent on the nature of the 6-alkylidene s

Full text of DOI:10.1021/jm00397a036

Products guided by the article

Product name:(8S,8aS)-8-hydroxy-8-methyl-6(Z)-<6'-oxo-2'(R),5'-dimethyl-7'(S)-<(benzyloxy)methoxy>-4'(E)-octenylidene>octahydroindolizidine

Cas No:112320-41-9

R&D Labs maybe for 112320-41-9

China Synchem Technology Co.,Ltd

website:http://www.cnsynchem.com

Contact:+86-0552-4929311

Address:No.217 Daqing Road
Hubei Vanz Pharm Co.,Ltd

website:http://www.vanzpharm.com/en/index.html

Contact:86-27-84492310

Address:FANHU INDUSTRY PARK
BIOS CHEMICALS

Contact:+33-5-34012600

Address:28 ZA des Pignès
Fuxin Jintelai Fluorin Chemical Co., Ltd.

Contact:+86-0418-8229599

Address:, 7th Huagong Road, Fluorine industry development zone (Yimatu Town,Fumeng County),Fuxin City, Liaoning Province, China
Okeanos Tech.Co.,LTD

Contact:+86-10-62651721

Address:29 Yongxing Road, Daxing District,Beijing China

Relevant to this article

Molecular structure of wlbb, a bacterial N -acetyltransferase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D -mannuronic acid

Doi:10.1021/bi1005738
(2010)
Syntheses with Nitriles, LXXV. The Reactivity of the Dimers of Malononitrile and Cyanoacetate with Dimethylformamide-dimethylacetal

Doi:10.1007/BF00809673
(1987)
Synthesis, Reactivity, Functionalization, and ADMET Properties of Silicon-Containing Nitrogen Heterocycles

Doi:10.1021/jacs.8b03187
(2018)
Intramolecular cyclization of ethyl ω-(5-amino-4-aminocarbonylimidazol-lyl)carboxylates

Doi:10.1002/jhet.5570240444
(1987)
Synthesis and structural properties of novel polycyclic aromatic compounds using photo-induced cyclisation of 2,7-di-tert-butyl-4-(phenylethenyl)pyrenes

Doi:10.3184/030823408X338710
(2008)
The total large-scale synthesis of argiopine

Doi:10.1134/S1068162009060120
(2009)

Article Doi