Quinazoline antifolate thymidylate synthase inhibitors: nitrogen, oxygen, sulfur, and chlorine substituents in the C2 position

DOI: 10.1021/jm00123a010

Source and publish data:

Journal of Medicinal Chemistry p. 569 - 575 (1989)

Update date:2022-09-26

Topics:

Authors:

Marsham Marsham

Chambers

Hayter Hayter

Hughes Hughes

Jackman Jackman

O'Connor

Bishop Bishop

Calvert Calvert

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00123a010

The synthesis of 16 new N¹⁰-propargylquinazoline antifolates with methylamino, ethylamino, (2-aminoethyl)amino, [2-(dimethylamino)ethyl]amino, (2-hydroxyethyl)amino, (carboxymethyl)amino, dimethylamino, imidazol-1-yl, methoxy, ethoxy, phenoxy,

Full text of DOI:10.1021/jm00123a010

Products guided by the article

Product name:Quinazoline, 6-methyl-2,4-diphenoxy-

Cas No:112888-68-3

R&D Labs maybe for 112888-68-3

H&Y International Group Ltd

Contact:+86-571-86491666

Address:SHI XIANG ROAD
Sarchem Laboratories, Inc.

Contact:732.938.2777

Address:5012 Industrial Road Farmingdale, NJ 07727
Shanghai Mintchem Development ., Ltd

Contact:0086 21 5190 8570

Address:R602,4#,89Nong, Mudan Road Pudong Shanghai China
Shandong Topscience Biotech Co., Ltd.

Contact:0633-2619278

Address:No. 98 Lanshan West Road, Lanshan District, Rizhao, Shandong Province, P.R. of China
Jiangsu Taihu New Materials Holding Co., Ltd

Contact:+86-519-86160108

Address:Xueyan Town, Changzhou City, Jiangsu Province, 213169, China

Relevant to this article

Intermolecular couplization and cyclization of chalcones promoted by samarium in DMF

Doi:10.1080/00397910802431164
(2009)
Preparation, Crystal Structure, and Magnetic Properties of an Oligonuclear Complex with 12 Coupled Spins and an S=12 Ground State

Doi:10.1021/ja00217a017
(1988)
METALLORGANISCHE LEWIS-SAEUREN. XXVII. METALLORGANISCHE VERBINDUNGEN MIT ANIONEN DER FLUOROSULFONSAEURE, SOWIE VON PERFLUORIERTEN SULFON- UND CARBONSAEUREN

Doi:10.1016/0022-328X(87)85026-X
(1987)
POLYAZA-MACROCYCLES OF CYCLOPHANE TYPE: SYNTHESIS, STRUCTURE OF A CHLOROFORM INCLUSION COMPLEX AND ANION BINDING.

Doi:10.1016/S0040-4039(00)96334-2
(1987)
Gold-catalyzed substitution reaction with ortho-alkynylbenzoic acid alkyl ester as an efficient alkylating agent

Doi:10.1016/j.tet.2008.12.033
(2009)
Cycloaddition Reactions of α-Keto Imines. Regio- and Stereoselectivities in the Dienic and Dienophilic Additions to Conjugated Dienes

Doi:10.1021/jo00245a023
(1988)

Article Doi