C-CENTRED OPTICALLY ACTIVE ORGANOSILANES,1. SYNTHESIS OF NEW SILYLATED CHIRAL AUXILIARIES.

Article abstract of DOI:10.1016/S0040-4039(00)95888-X

Different silylating reagents with an optically active ligand bonded to the silicon centre have been synthesized starting from (1R)(-)myrtenal.The key step of the synthesis is the stereocontrolled 1,4 addition of phenyldimethylsilyl-cuprate to the α,β unsaturated aldehyde.