Tetrahedron p. 2293 - 2302 (1987)
Update date:2022-07-30
Topics:
Carboni, Bertrand
Toupet, Loic
Carrie, Robert
Depending on the nature of the substituent R2, diaziridines (I) react with dimethylacetylenedicarboxylate to give either iminoenamines or enamidines. When R1 = H and R2 = CH3 only one diastereoisomer is transformed, i.e. 1' and, then, 1' is isolated in a pure form. The knowledge of the stereochemistry of and of the structure of the obtained products allow a discussion of the mechanism of the reaction. The addition of picric acid to a mixture of diaziridines 1' and 1' leads to the picrate of 1' which, on treatment with sodium carbonate, gives this isomer pure.
Engineering Research Center of Pesticide, Heilongjiang Province
Contact:+86-451-86609001
Address:No.74 of Xuefu Road, Nangang District,
Zhejiang Haizhou Pharmaceutical Co., Ltd.
website:https://www.haizhoupharma.com/
Contact:+86-576-88221016
Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Contact:86-575-86132822，86-575-86085355
Address:No.418 Dadao West Road,Qixing Street,Xinchang, Zhejiang Province, China.
website:http://www.orchid-chem.com
Contact:+86-571-85395792
Address:607, North Zhongshan Road, Hangzhou 310000 China
website:http://www.josunpharma.com
Contact:+86-311-80715268 80766839
Address:No.39, Zhaiying Street, Shijaizhuang,Hebei,China
Doi:10.1021/ja810043d
(2009)Doi:10.1002/ejic.200700749
(2008)Doi:10.1021/jf404130d
(2014)Doi:10.1021/jo802819p
(2009)Doi:10.1055/s-0036-1588440
(2017)Doi:10.1016/j.ejmech.2011.01.060
(2011)
