Tetrahedron p. 1127 - 1134 (1988)
Update date:2022-08-02
Topics:
Viger, Antoinette
Coustal, Suzy
Perard, Serge
Marquet, Andree
The synthesis of 18 vinyl and 18 ethynylprogesterone 1 and 2 is described. The reported data emphasize the decisive role played by the protective group on carbon 3 in the course of reactions taking place at the angular 18 methyl group. Compounds 1 and 2, designed as kcat inhibitors of aldosterone biosynthesis late step show substantial in vitro activity.
View MoreTianjin Crest Pharmaceutical R&D Co., Ltd. （Tianjin Yao Technology Development Co., Ltd.）(expird)
Contact:+86-22-66211386
Address:Building B5-405, No, 80 4th Avenue, TEDA, Tianjin, China P.R. 300457
Nanjing Legend Pharmaceutical & Chemical Co., Ltd.
Contact:+86-25-83767696
Address:14-7 Zhongshan Lu Guluo District, Nanjing
Shangyu Sanhechemicals Co.,LTD.
Contact:86-0571-56696839
Address:Num.2952,Nanhuan Road,Binjiang District,Hangzhou,China
wuxi huabin bio-tech Co.,Ltd(expird)
Contact:86-0510-85133006
Address:hubin road NO157
ALPHA PHARMACEUTICAL CO，LTD JIANGSU
Contact:+86-527-84829968,+86-527-84829998
Address:suqian city
Doi:10.1016/j.ejmech.2008.10.018
(2009)Doi:10.1007/BF00904729
(1964)Doi:10.1016/j.tetlet.2009.03.185
(2009)Doi:10.1016/j.tet.2009.03.041
(2009)Doi:10.1039/c39870001472
(1987)Doi:10.1007/s00044-009-9192-x
(2010)
