Tetrahedron p. 1127 - 1134 (1988)
Update date:2022-08-02
Topics:
Viger, Antoinette
Coustal, Suzy
Perard, Serge
Marquet, Andree
The synthesis of 18 vinyl and 18 ethynylprogesterone 1 and 2 is described. The reported data emphasize the decisive role played by the protective group on carbon 3 in the course of reactions taking place at the angular 18 methyl group. Compounds 1 and 2, designed as kcat inhibitors of aldosterone biosynthesis late step show substantial in vitro activity.
View Morewebsite:http://www.vanzpharm.com/en/index.html
Contact:86-27-84492310
Address:FANHU INDUSTRY PARK
Shandong LuZhou Amino Acid Co., Ltd
Contact:86-539-2218025
Address:yishui economic and technical development zone zhenxing south road
Hubei Onward Bio-Development Co., Ltd.
Contact:+86-718-8417012
Address:No.517,Shizhou Avenue,Enshi City,Hubei Province,China,445002
Shijiazhuang Yunxuan Im&Export Co.,Ltd.
Contact:+86-311-83037514
Address:No.6 Hongbin Road
Ningbo Inno Pharmchem Co., Ltd.
Contact:86-574-87319282
Address:6F-5,NO.163 RUIQING RD.,NINGBO 315000 CHINA
Doi:10.1016/j.ejmech.2008.10.018
(2009)Doi:10.1007/BF00904729
(1964)Doi:10.1016/j.tetlet.2009.03.185
(2009)Doi:10.1016/j.tet.2009.03.041
(2009)Doi:10.1039/c39870001472
(1987)Doi:10.1007/s00044-009-9192-x
(2010)
