Base induced opening of 2,3-epoxychlorides: An efficient preparation of trans-chlorovlnyl alcohols

DOI: 10.1016/S0040-4039(00)97658-5

Source and publish data:

Tetrahedron Letters p. 4495 - 4496 (1990)

Update date:2022-08-05

Topics:

Authors:

Yada Yada

Deshpande, Prasad K.

Sharma Sharma

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Article abstract of DOI:10.1016/S0040-4039(00)97658-5

A highly efficient protocol for the sythesis of of chiral trans-1-chlorvinyl alcohols (2) from chiral 2,3-epoxychloride is described by using stoicheiometric amount of LiNH₂ or LDA.

Full text of DOI:10.1016/S0040-4039(00)97658-5

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