1,2,4-Triazoles, II Synthesis of 1,5-Diphenyl-3-trifluoromethyl-1H-1,2,4-triazoles

DOI: 10.1007/BF00810261

Source and publish data:

Monatshefte fur Chemie p. 349 - 354 (1988)

Update date:2022-08-02

Topics:

Authors:

Czollner, Laszlo

Szilagyi, Geza

Lango, Jozsef

Janaky, Judit

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Article abstract of DOI:10.1007/BF00810261

Reaction of substituted phenylhydrazines 1a-f with methyl trifluoroacetimidate 2 gives via the amidrazones 3 after treatment with benzoyl chlorides 4 the triazoles 5a-f which showed an anti-inflammatory effect. - Keywords: Cyclization; Anti-inflammatory effect; 1,5-Diphenyltriazole; Trifluoroacetamidrazone

Full text of DOI:10.1007/BF00810261

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