SYNTHESIS OF A PHOSPHORAMIDITE OF 2'-DEOXY-5,6-DIHYDRO-5-AZACYTIDINE. ITS POTENTIAL APPLICATION IN THE SYNTHESIS OF DNA CONTAINING DIHYDRO-5-AZA- AND 5-AZACYTOSINE BASES.

DOI: 10.1016/S0040-4039(00)82037-7

Source and publish data:

Tetrahedron Letters p. 1767 - 1770 (1988)

Update date:2022-07-29

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Authors:

Goddard, Amanda J.

Marquez, Victor E.

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Article abstract of DOI:10.1016/S0040-4039(00)82037-7

A novel phosphoramidite (9) has been synthesized and shown to be an efficient coupling reagent for the synthesis of oligonucleotide fragments containing the modified base 5,6-dihydro-5-azacytosine.With a model dihydro-5-azacytosine/thymine dimer (12), oxi

Full text of DOI:10.1016/S0040-4039(00)82037-7

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