Journal of the Chemical Society. Chemical communications p. 524 - 526 (1988)
Update date:2022-07-29
Topics:
Tanaka, Kiyoshi
Kimachi, Tetsutaro
Kawase, Masahiro
Yoneda, Fumio
The first total synthesis of Methanobacterium redox coenzyme Factor 420 (F20) has been achieved by the formation of a phosphotriester bond between a protected 10-D-ribityl-8-hydroxy-5-deazaisoalloxazine moiety and a peptide moiety, (L-lactate-γ-L-glutamyl)-L-glutamic acid tribenzyl ester, by the phosphite triester approach using β,β,β-trichloroethyl phosphorodichloridite, followed by successive deprotection.
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Doi:10.1021/ja803187x
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(2009)Doi:10.1016/S0040-4020(01)85964-0
(1988)Doi:10.1016/j.tet.2009.05.025
(2009)Doi:10.1055/s-1988-27590
(1988)Doi:10.1016/j.tetlet.2012.05.130
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