Synthesis of novel bifunctional chelators and their use in preparing monoclonal antibody conjugates for tumor targeting

DOI: 10.1021/jm00121a042

Source and publish data:

Journal of Medicinal Chemistry p. 236 - 243 (1989)

Update date:2022-08-04

Topics:

Authors:

Westerberg

Carney Carney

Rogers Rogers

Kline Kline

Johnson Johnson

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00121a042

Bifunctional derivatives of the chelating agents ethylenediaminetetraacetic acid and diethylenetriaminepentaacetic acid, in which a p-isothiocyanatobenzyl moiety is attached at the methylene carbon atom of one carboxymethyl arm, was synthesized by reducti

Full text of DOI:10.1021/jm00121a042

Products guided by the article

Product name:N-(carboxymethyl)-N-(2-((2'-(bis(carboxymethyl)amino)ethyl)(carboxymethyl)amino)ethyl)-3-(4-isothiocyanatophenyl)alanine trihydrochloride

Cas No:117526-32-6

R&D Labs maybe for 117526-32-6

Zhengzhou Minzhong Pharmaceutical Co.,ltd

Contact:0086-371-65797115

Address:15/F,Jiangshan Bldg, NO.126 Huanghe Road,Zhengzhou, China
Beijing Mediking Biopharm Co., Ltd.

Contact:+86-10-89753524/81760121/81769521

Address:Hongxianghong Incubator, Beiqijia Town, Changping district, Beijing, China
Hangzhou Ocean Chemical Co., Ltd.

website:http://www.hzoceanchem.com

Contact:+86-571-88025872, 28272092, 28272096

Address:Room 623 ,Building No 1 , COFCO Radius Commercial Center Xiwen Road, Xiacheng District, Hangzhou, Zhejiang Province, China
Taizhou Shengxing Chempharm Co.,Ltd

Contact:+86-576-88516600

Address:Yantou Chemical Zone Jiaojiang Taizhou Zhejiang China
Chongqing Werlchem Fine Chemical Co. Ltd

Contact:+86-23-67521957

Address:NO.15,Fortune Road,Yubei District,401121,Chongqing,China

Relevant to this article

A crystallizable dinuclear tuck-in-tuck-over tuck-over dialkyl tren uranium complex and double dearylation of BPh₄^- to give the BPh₂-functionalized metallocycle [U{N(CH₂CH ₂NSiMe₃)₂

Doi:10.1021/ja904459q
(2009)

Chelation and extraction of copper(II) with 5-pyrazolone-based Schiff bases

Doi:10.1080/00958972.2011.553675
(2011)
Synthesis of Diaryl Ethers, Diaryl Thioethers, and Diarylamines Mediated by Potassium Fluoride-Alumina and 18-Crown-6

Doi:10.1021/jo00064a004
(1993)
STEREOCHEMICALLY CONTROLLED SYNTHESIS OF UNSATURATED 2,5-DIALKYL FURANES

Doi:10.1016/S0040-4039(00)82094-8
(1988)
Renaissance of traditional organic reactions under microfluidic conditions: A new paradigm for natural products synthesis

Doi:10.1021/op900084f
(2009)
Doi:10.1016/S0040-4020(01)98320-6
(1965)

Article Doi