Synthesis of substituted 2-ethoxycarbonyl- and 2-carboxyquinoxalin -3 ones for evaluation of antimicrobial and anticancer activity

DOI: 10.1016/S0014-827X(98)00044-5

Source and publish data:

Il Farmaco p. 455 - 461 (1998)

Update date:2022-08-05

Topics: Synthesis Antimicrobial Substituted Anticancer Activity

Authors:

Sanna, Paolo

Carta, Antonio

Loriga, Mario

Zanetti, Stefania

Sechi, Leonardo

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Article abstract of DOI:10.1016/S0014-827X(98)00044-5

A series of variously substituted quinoxalin-3-ones bearing an ethoxycarbonyl or carboxy group in the C-2 position has been prepared and their structures proved by ¹H NMR spectroscopy. The obtained compounds were investigated in vitro for antimicrobial and anticancer activities. Preliminary results showed a moderate activity against a few strains of bacteria but no significant anticancer and anti-HIV activity.

Full text of DOI:10.1016/S0014-827X(98)00044-5

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