Il Farmaco p. 455 - 461 (1998)
Update date:2022-08-05
Topics: Synthesis Antimicrobial Substituted Anticancer Activity
Sanna, Paolo
Carta, Antonio
Loriga, Mario
Zanetti, Stefania
Sechi, Leonardo
A series of variously substituted quinoxalin-3-ones bearing an ethoxycarbonyl or carboxy group in the C-2 position has been prepared and their structures proved by 1H NMR spectroscopy. The obtained compounds were investigated in vitro for antimicrobial and anticancer activities. Preliminary results showed a moderate activity against a few strains of bacteria but no significant anticancer and anti-HIV activity.
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Doi:10.1021/ja00185a042
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