Discovery of small peptides derived from embryonic lethal abnormal vision proteins structure showing RNA-stabilizing properties

DOI: 10.1021/jm900741e

Source and publish data:

Journal of Medicinal Chemistry p. 5017 - 5019 (2009)

Update date:2022-07-31

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Authors:

Rossi, Daniela

Amadio, Marialaura

Baraglia, Anna Carnevale

Azzolina, Ornella

Ratti, Antonia

Govoni, Stefano

Pascale, Alessia

Collina, Simona

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Article abstract of DOI:10.1021/jm900741e

Four peptides corresponding to highly conserved motives within the first two RNA recognition motif-type domains of ELAV proteins were prepared, and their effect on the stability of NOVA-1 and VEGF ELAV-target mRNAs was evaluated. Biological results show t

Full text of DOI:10.1021/jm900741e

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