Methylation and Hydroxymethylation of Allylic Alcohols via Radical Cyclization. Methodology for Stereoselective Construction of an Aliphatic Chain in Application to Sterol Synthesis

DOI: 10.1021/jo00298a020

Source and publish data:

Journal of Organic Chemistry p. 3484 - 3492 (1990)

Update date:2022-08-03

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Authors:

Kurek-Tyrlik, Alicja

Wicha, Jerzy

Zarecki, Andrzej

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Article abstract of DOI:10.1021/jo00298a020

Reductive free-radical cyclization of (bromomethyl)dimethylsilyl derivatives (6b-9b) of allylic alcohols (6a-9a) was studied to evaluate the scope of a novel method of methylation and hydroxymethylation of allylic alcohols.Treatment of (bromomethyl)dimeth

Full text of DOI:10.1021/jo00298a020

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