Chemistry of Heterocyclic Compounds p. 914 - 919 (1988)
Update date:2022-09-26
Topics:
Dozorova, E. N.
Solov'eva, N. P.
Granik, V. G.
The reaction of α-cyano-β-aminocrotonic ester with DMFA diethylacetal gives 1-ethoxycarbonyl-1-cyano-2-(N-dimethylaminomethylene)-amino-4-dimethylaminobutadiene, the reaction of which with ammonium acetate and amines leads to 4-methylenepyrimidine derivatives.Condensation of α-cyano-β-aminocrotonic ester with dimethylacetamide diethylacetal gave 2-(ethoxycarbonylcyano)methylene-4-dimethylamino-6-methylpyridine.It was found that in an alkaline medium, 1-benzyl-4-(ethoxycarbonylcyano)methylenepyrimidine recyclizes into 1-benzyl-3-cyano-4-amino-2-pyridone.
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Doi:10.1016/j.ica.2007.05.063
(2008)Doi:10.1021/acs.orglett.9b03004
(2019)Doi:10.1039/b306236h
(2003)Doi:10.1080/00397910802138785
(2008)Doi:10.1016/0031-9422(90)85165-C
(1990)Doi:10.1055/s-0037-1610877
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