Synthesis of antitumour carbon-bridged imidazopyridazine carbamates

DOI: 10.1002/ardp.19943270207

Source and publish data:

Archiv der Pharmazie p. 95 - 98 (1994)

Update date:2022-07-29

Topics:

Authors:

Denyer Denyer

Reddy Reddy

Jenkins Jenkins

Rapson Rapson

Watts Watts

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Article abstract of DOI:10.1002/ardp.19943270207

Two carbon-bridged analogues 11 and 15 of the potent microtubule inhibitor BW1069C85 (1) have been synthesised and evaluated for antitubulin and antitumour activity in vitro. Though the compounds were somewhat less potent than BW1069C85, significant activ

Full text of DOI:10.1002/ardp.19943270207

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