A VERSATILE SYNTHESIS OF CARBAPENEMS FROM SUBSTITUTED DIHYDROPYRANS

DOI: 10.1016/S0040-4039(00)82343-6

Source and publish data:

Tetrahedron Letters p. 6345 - 6348 (1988)

Update date:2022-08-04

Topics:

Authors:

Bayles, Richard

Flynn, Anthony P.

Galt, Ronald H.B.

Kirby, Susan

Turner, Ralph W.

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Article abstract of DOI:10.1016/S0040-4039(00)82343-6

Dihydropyrans (1) are converted by hydrolysis and reduction to δ-lactones (3), and then to azetidinones (5) which are key intermediates for the synthesis of carbapenems.

Full text of DOI:10.1016/S0040-4039(00)82343-6

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