Synthesis of 2,4-Dideoxy-4--α,β-D-erythro-pentofuranoses. The First P-in-Ring Sugar Analogues of 2-Deoxy-D-ribofuranose Type

Article abstract of DOI:10.1246/cl.1988.1575

Starting with 3-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose, methyl 2,4-dideoxy-4-<(methoxy)methyl- and cyclohexylphosphinyl>-D-glycero-pentopyranosides were prepared in a 9 step sequence (20-25percent overall yield).These were converted into the title compounds, which were characterized as the 1,3,5-tri-O-acetates.