Convenient electrophilic fluorination of functionalized aryl and heteroaryl magnesium reagents

DOI: 10.1002/anie.200905052

Source and publish data:

Angewandte Chemie - International Edition p. 2215 - 2218 (2010)

Update date:2022-08-05

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Authors:

Yamada, Shigeyuki

Gavryushin, Andrei

Knochel, Paul

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Article abstract of DOI:10.1002/anie.200905052

"Chemical Equation Presented" Cive me an "F": Electrophilic fluorination of various aromatic and heteroaromatic Grignard reagents is smoothly performed with (PhSO₂)₂NF as fluorinating agent in a 4:1 mixture of CH₂Cl₂/ perfluorodecalin (see scheme). This solvent system allows minimization of most side reactions.

Full text of DOI:10.1002/anie.200905052

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