Journal of Medicinal Chemistry p. 2134 - 2137 (1989)
Update date:2022-08-05
Topics:
Hughes, Philip
Virgilio, John De
Humber, Leslie G.
Chau, Thuy
Weichman, Barry
Neuman, Glen
The synthesis of 4,6-diethyl-1,3,4,5-tetrahydropyrano<4,3-b>indole-4-acetic acid, an isomer of the antiinflammatory agent etodolac, is described.The compound was found to have an ED50 of 3 mg/kg po in the rat curative adjuvant arthritis assay,
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