Journal of the Chemical Society. Chemical communications p. 1370 - 1371 (1989)
Update date:2022-09-26
Topics:
Jones, David W.
Thompson, Adrian M.
The alkene (2) obtained directly from the reaction of dimethyl maleate with the pyrone (1) is converted into (+/-)-podophyllotoxin (12) in seven steps and 24percent overall yield; novel steps include the epimerisation of (9) at C-3 using 1,8-diazabicyclo<
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Doi:10.3390/molecules24203658
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