SYNTHESIS OF SUBSTITUTED SPIRODECA-3,6,9-TRIENE-2,8-DIONES: AN EXPEDITIOUS ROUTE TO THE SPIRODECANE TERPENE SKELETON

Article abstract of DOI:10.1016/S0040-4039(00)99532-7

Substituted spiro<4,5>decanes are prepared in two steps in fair to moderate yield.A substituted 4-methoxyphenylacetyl chloride, prepared from the corresponding acid, is reacted with a substituted acetylene (or acetylene gas) in the presence of aluminium c